{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T15:13:37Z","timestamp":1775574817389,"version":"3.50.1"},"reference-count":36,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,1,8]]},"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>Non-compaction of ventricular myocardium is a rare cardiomyopathy involving an early arrest of normal compaction of myocardium during fetal ontogenesis. Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary nephropathy characterised by multiple renal cysts replacing the renal parenchyma and extrarenal manifestations. Here, we report a case of 65-year-old man, chronic smoker, presented with sudden onset right brachial monoparesis, exertional dyspnoea, orthopnoea, bipedal swelling and diagnosed as a case of ADPKD with left ventricular non-compaction cardiomyopathy with acute left ventricular failure and cardiogenic cerebral embolism (no evidence of atrial fibrillation); based on characteristic appearance on two-dimensional echocardiography and cardiac magnetic resonance. The patient was managed with guideline-directed pharmacotherapy for heart failure and anticoagulation as a secondary stroke prevention measure. Through this case report, we try to discuss the association between two rare entities and individualisation of treatment options available as a case-based approach, as no standard treatment guidelines are available.<\/jats:p>","DOI":"10.1136\/bcr-2019-232458","type":"journal-article","created":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T04:35:14Z","timestamp":1579754114000},"page":"e232458","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Non-compaction of ventricular myocardium with polycystic kidney disease with cardiogenic cerebral embolism"],"prefix":"10.1136","volume":"13","author":[{"given":"Monu","family":"Rani","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Medicine Unit, Pt. B D Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India, Rohtak, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Rajput","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Medicine Unit, Pt. B D Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India, Rohtak, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanat","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Medicine Unit, Pt. B D Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India, Rohtak, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakesh","family":"Garg","sequence":"additional","affiliation":[{"name":"Internal Medicine, Pt. B D Sharma Postgraduate Institute of Medical Sciences Rohtak, Rohtak, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,1,22]]},"reference":[{"key":"2025082801023053000_13.1.e232458.1","doi-asserted-by":"publisher","DOI":"10.1136\/heart.86.1.e4"},{"key":"2025082801023053000_13.1.e232458.2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2018060590"},{"key":"2025082801023053000_13.1.e232458.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00755-5"},{"key":"2025082801023053000_13.1.e232458.4","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.13.3.273"},{"key":"2025082801023053000_13.1.e232458.5","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2018-000869","article-title":"Prevalence of left ventricle non-compaction criteria in adult patients with bicuspid aortic valve versus healthy control subjects","volume":"5","author":"Shen","year":"2018","journal-title":"Open Heart"},{"key":"2025082801023053000_13.1.e232458.6","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm342"},{"key":"2025082801023053000_13.1.e232458.7","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.174287"},{"key":"2025082801023053000_13.1.e232458.8","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.5.841"},{"key":"2025082801023053000_13.1.e232458.9","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-193204000-00003"},{"key":"2025082801023053000_13.1.e232458.10","unstructured":"Collins P . 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