{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:06:16Z","timestamp":1756339576035,"version":"3.44.0"},"reference-count":31,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,2,19]]},"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:p>A 30-year-old man with a history of severe right iliac fossa pain was referred to the surgical emergency unit. His symptoms began 3 days prior as mild, non-specific abdominal pain which progressively localised to the right iliac fossa and worsened in severity. Investigations were suggestive of acute appendicitis, and therefore a laparoscopic appendicectomy was planned. Laparoscopy revealed a thickened, necrotic appendix with a mass at the base of the appendix, in keeping with the appearance of an appendiceal malignancy. Subsequently a right hemicolectomy was performed. Histology revealed active chronic inflammation and granulomas highly suggestive of appendiceal Crohn\u2019s disease. Since, the patient has made a good recovery and presently shows no further signs of Crohn\u2019s disease. This case is demonstrative of one of many rare findings on histological examination of the appendix. It emphasises the need for a wide differential when investigating right iliac fossa pain.<\/jats:p>","DOI":"10.1136\/bcr-2019-232549","type":"journal-article","created":{"date-parts":[[2020,2,28]],"date-time":"2020-02-28T14:25:14Z","timestamp":1582899914000},"page":"e232549","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Appendiceal Crohn\u2019s disease: a rare differential of right iliac fossa pain"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9029-6981","authenticated-orcid":false,"given":"Adam James","family":"Crellin","sequence":"first","affiliation":[{"name":"Medical Sciences Division, Oxford University, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Musbahi","sequence":"additional","affiliation":[{"name":"Oxford University Clinical Academic Graduate School, Oxford University, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha","family":"Onwu","sequence":"additional","affiliation":[{"name":"Department of Cellular Pathology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,2,28]]},"reference":[{"key":"2025082711165912000_13.2.e232549.1","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900235"},{"key":"2025082711165912000_13.2.e232549.2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijsu.2016.05.030","article-title":"One year negative appendicectomy rates at a district general Hospital: a retrospective cohort study","volume":"31","author":"Lim","year":"2016","journal-title":"Int J Surg"},{"key":"2025082711165912000_13.2.e232549.3","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-006-1855-5"},{"key":"2025082711165912000_13.2.e232549.4","doi-asserted-by":"publisher","DOI":"10.1308\/003588410X12518836439920"},{"key":"2025082711165912000_13.2.e232549.5","doi-asserted-by":"publisher","DOI":"10.1258\/shorts.2010.010079"},{"key":"2025082711165912000_13.2.e232549.6","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1111\/ans.12211","article-title":"Does an acute surgical model increase the rate of negative appendicectomy or perforated appendicitis?","volume":"83","author":"Brockman","year":"2013","journal-title":"Australian and New Zealand Journal of Surgery"},{"key":"2025082711165912000_13.2.e232549.7","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9201"},{"key":"2025082711165912000_13.2.e232549.8","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1308\/003588413X13511609957371","article-title":"The diagnostic value of white cell count, C-reactive protein and bilirubin in acute appendicitis and its complications","volume":"95","author":"Panagiotopoulou","year":"2013","journal-title":"Ann R Coll Surg Engl"},{"key":"2025082711165912000_13.2.e232549.9","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1007\/s00384-014-1934-7","article-title":"Histopathological findings in appendectomy specimens: a study of 24,697 cases","volume":"29","author":"Charfi","year":"2014","journal-title":"Int J Colorectal Dis"},{"key":"2025082711165912000_13.2.e232549.10","doi-asserted-by":"crossref","first-page":"888","DOI":"10.12998\/wjcc.v2.i12.888","article-title":"Appendiceal Crohn's disease clinically presenting as acute appendicitis","volume":"2","author":"Han","year":"2014","journal-title":"World J Clin Cases"},{"key":"2025082711165912000_13.2.e232549.11","first-page":"891","article-title":"Nonspecific granulomatous inflammation (Crohn's disease) of the appendix; 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