{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T10:25:35Z","timestamp":1769163935672,"version":"3.49.0"},"reference-count":15,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,1,26]]},"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:p>Colistin-induced nephrotoxicity is commonly associated with elevation of serum creatinine level or a reduction of urine output. Uncommonly, tubulopathy associated with colistin has been reported. Here we present a unique case of a 46-year-old man who developed polyuria, hypokalaemia, hypocalcaemia, hypomagnesemia and metabolic alkalosis after 3\u2009days of therapy with intravenous colistimethate sodium. After ruling out other causes, a diagnosis of colistin-induced acquired Bartter syndrome was made. The patient required daily aggressive intravenous repletion of fluids and electrolytes. However, polyuria and metabolic abnormalities abated only after drug discontinuation.<\/jats:p>","DOI":"10.1136\/bcr-2019-232630","type":"journal-article","created":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T04:35:13Z","timestamp":1580963713000},"page":"e232630","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Colistin-induced acquired Bartter-like syndrome: an unusual cause of meltdown"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5192-6901","authenticated-orcid":false,"given":"Mohammad","family":"Tabish","sequence":"first","affiliation":[{"name":"Medicine, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manjit","family":"Mahendran","sequence":"additional","affiliation":[{"name":"Medicine, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7498-9112","authenticated-orcid":false,"given":"Animesh","family":"Ray","sequence":"additional","affiliation":[{"name":"Medicine, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naval Kishore","family":"Vikram","sequence":"additional","affiliation":[{"name":"Medicine, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,2,5]]},"reference":[{"key":"2025082713054587000_13.2.e232630.1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/MOP.0000000000000447","article-title":"Bartter\u2019s and Gitelman\u2019s syndrome","volume":"29","author":"Seyberth","year":"2017","journal-title":"Curr Opin Pediatr"},{"key":"2025082713054587000_13.2.e232630.2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(06)70580-1"},{"key":"2025082713054587000_13.2.e232630.3","doi-asserted-by":"publisher","DOI":"10.1186\/cc3995"},{"key":"2025082713054587000_13.2.e232630.4","doi-asserted-by":"crossref","DOI":"10.1186\/2110-5820-1-14","article-title":"Renal and neurological side effects of colistin in critically ill patients","volume":"1","author":"Spapen","year":"2011","journal-title":"Ann Intensive Care"},{"key":"2025082713054587000_13.2.e232630.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2005.09.004"},{"key":"2025082713054587000_13.2.e232630.6","doi-asserted-by":"publisher","DOI":"10.1086\/599225"},{"key":"2025082713054587000_13.2.e232630.7","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr475"},{"key":"2025082713054587000_13.2.e232630.8","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-200503000-00007"},{"key":"2025082713054587000_13.2.e232630.9","doi-asserted-by":"publisher","DOI":"10.1159\/000094001"},{"key":"2025082713054587000_13.2.e232630.10","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1007\/s00508-011-0011-2","article-title":"Recurrent symptomatic hypocalcemia during rifampicin therapy for brucellosis","volume":"123","author":"Torun","year":"2011","journal-title":"Wien Klin Wochenschr"},{"key":"2025082713054587000_13.2.e232630.11","first-page":"355","article-title":"A rare complication of antibiotic (piperacillin\/tazobactam) therapy: resistant hypokalemia","volume":"3","author":"Kutluturk","year":"2012","journal-title":"J Med Cases"},{"key":"2025082713054587000_13.2.e232630.12","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02799-9"},{"key":"2025082713054587000_13.2.e232630.13","doi-asserted-by":"crossref","first-page":"102","DOI":"10.33590\/emjnephrol\/10312410","article-title":"Prolonged intravenous colistin use associated with acquired Bartter-like syndrome in an adult patient: a case report","volume":"6","author":"Choksi","year":"2018","journal-title":"EMJ Nephrol"},{"key":"2025082713054587000_13.2.e232630.14","doi-asserted-by":"crossref","first-page":"411","DOI":"10.3109\/0886022X.2012.761084","article-title":"Acquired Bartter-like syndrome associated with colistin use in a preterm infant","volume":"35","author":"Cakir","year":"2013","journal-title":"Ren Fail"},{"key":"2025082713054587000_13.2.e232630.15","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s40800-017-0052-1","article-title":"Reversible hypokalemia and Bartter-like syndrome during prolonged systemic therapy with colistimethate sodium in an adult patient","volume":"4","author":"Kamal Eldin","year":"2017","journal-title":"Drug Saf Case Rep"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-232630","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:05:54Z","timestamp":1756325154000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-232630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":15,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,2,5]]},"published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1136\/bcr-2019-232630"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-232630","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2]]}}}