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After extensive complementary workup, which excluded new neurological lesions or endocrinological conditions, hypothalamic dysfunction was assumed to be the cause of this syndrome. She was successfully treated with midodrine and on-demand captopril, which resulted in adequate control of her blood pressure. This case highlights the rare and unpredictable consequences of damage to the hypothalamus, depicting the favourable result of a heretofore unpublished medical approach.<\/jats:p>","DOI":"10.1136\/bcr-2019-232767","type":"journal-article","created":{"date-parts":[[2020,6,18]],"date-time":"2020-06-18T06:18:09Z","timestamp":1592461089000},"page":"e232767","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Dysautonomia secondary to third ventriculostomy successfully managed with midodrine"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2820-3259","authenticated-orcid":false,"given":"Torcato","family":"Moreira Marques","sequence":"first","affiliation":[{"name":"Internal Medicine Department, Hospital de Santa Marta, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Almeida","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Hospital de Santa Marta, Lisboa, Portugal"},{"name":"NOVA Medica School, Faculdade de Ci\u00eancias M\u00e9dicas da Universidade NOVA de Lisboa, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana","family":"Pinheiro","sequence":"additional","affiliation":[{"name":"Endocrinology Department, Instituto Portugu\u00eas de Oncologia de Lisboa Francisco Gentil EPE, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula Oliveira","family":"Nascimento","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Hospital de Santa Marta, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,6,17]]},"reference":[{"key":"2025082711205679000_13.6.e232767.1","unstructured":"Melmed S , Polonsky K , Larsen P , et al . 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