{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T07:39:25Z","timestamp":1772264365432,"version":"3.50.1"},"reference-count":7,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,2,11]]},"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:p>We report a case of \u2018occult\u2019 bilateral optic nerve aplasia (ONA) where pituitary dysfunction was discovered subsequently. The initial ultrasonography had missed ONA in a child with bilateral microcornea, small non-dilating pupils and roving eye movements. Due to presence of relevant clinical signs in this case, ONA was re-evaluated with MRI, and was subsequently discovered to be associated with life-endangering hypopituitarism. This case raises the possible underestimation of ONA, and hence also the risk of missing life-threatening endocrine disorders.<\/jats:p>","DOI":"10.1136\/bcr-2019-232839","type":"journal-article","created":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T04:29:35Z","timestamp":1582259375000},"page":"e232839","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["A case of occult bilateral optic nerve aplasia with pituitary dysfunction: hidden anomaly missed on ultrasound"],"prefix":"10.1136","volume":"13","author":[{"given":"Harsha","family":"Saxena","sequence":"first","affiliation":[{"name":"Ophthalmology, All India Institute of Medical Science Bhopal, Bhopal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brijesh","family":"Takkar","sequence":"additional","affiliation":[{"name":"Ophthalmology, All India Institute of Medical Science Bhopal, Bhopal, India"},{"name":"Smt Kanuri Santhamma Centre for Vitreoretinal Diseases, LV Prasad Eye Institute, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amber","family":"Kumar","sequence":"additional","affiliation":[{"name":"Pediatrics, All India Institute of Medical Sciences Bhopal, Bhopal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6640-3863","authenticated-orcid":false,"given":"Radha","family":"Sarawagi","sequence":"additional","affiliation":[{"name":"Radiology, All India Institute of Medical Science Bhopal, Bhopal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,2,20]]},"reference":[{"key":"2025082708405622000_13.2.e232839.1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.122.1.125"},{"key":"2025082708405622000_13.2.e232839.2","doi-asserted-by":"crossref","unstructured":"Brodsky MC , Baker RS , Hamed LM . 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Pediatric ophthalmology and strabismus. 3rd edn. Baltimore: Elsevier-Saunders, 2005: 637\u20138."},{"key":"2025082708405622000_13.2.e232839.7","doi-asserted-by":"crossref","first-page":"106","DOI":"10.4103\/1658-354X.197350","article-title":"Septo-Optic dysplasia\/de Morsier's syndrome","volume":"11","author":"Reis","year":"2017","journal-title":"Saudi J Anaesth"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-232839","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:41:02Z","timestamp":1756309262000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-232839"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":7,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,2,20]]},"published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1136\/bcr-2019-232839"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-232839","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2]]}}}