{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T19:49:33Z","timestamp":1775850573416,"version":"3.50.1"},"reference-count":17,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,12,6]]},"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>Immune-mediated reactions to dairy products may vary depending on the mammalian source. We present a case of anaphylaxis to goat\/sheep's milk with tolerance to cow\u2019s milk. A 4-year-old boy of Eastern European descent presented with gastrointestinal and respiratory symptoms within minutes after eating a goat\/sheep\u2019s milk-derived food product. The tryptase level measured 1 hour post initial symptoms and 1\u2009month after the allergic reaction were 14.6\u2009\u00b5g\/L and 5.1\u2009\u00b5g\/L, respectively (norm: 0.0\u201313.5\u2009\u00b5g\/L), confirming the diagnosis of anaphylaxis. A skin prick test performed 1\u2009month after the reaction was highly positive for goat\/sheep\u2019s milk, but negative for cow\u2019s milk. Skin prick tests may establish a life-threatening goat\/sheep\u2019s milk allergy. Goat\/sheep\u2019s milk allergy should always be considered in cow\u2019s milk-tolerant patients who present with an allergic reaction to dairy products, or when undergoing\/have completed of oral immunotherapy for cow\u2019s milk allergy.<\/jats:p>","DOI":"10.1136\/bcr-2019-232844","type":"journal-article","created":{"date-parts":[[2020,1,9]],"date-time":"2020-01-09T04:55:28Z","timestamp":1578545728000},"page":"e232844","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Anaphylaxis to goat\/sheep\u2019s milk in a 4-year-old boy tolerant to cow\u2019s milk"],"prefix":"10.1136","volume":"13","author":[{"given":"Pasquale","family":"Mul\u00e9","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Allergy, Immunology and Dermatology, Montreal Children's Hospital, Montreal, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofianne","family":"Gabrielli","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Allergy, Immunology and Dermatology, Montreal Children's Hospital, Montreal, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Upton","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Immunology and Allergy, Hospital for Sick Children, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abrams","family":"EM","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Section of Allergy and Clinical Immunology, University of Manitoba, Winnipeg, Manitoba, Canada"},{"name":"Department of Pediatrics, Division of Allergy and Immunology, The University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moshe","family":"Ben-Shoshan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Allergy, Immunology and Dermatology, Montreal Children's Hospital, Montreal, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,1,8]]},"reference":[{"key":"2025082708083170000_13.1.e232844.1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2013.12.395","article-title":"Cross-Desensitization to goat and sheep milk protein in cow's milk protein desensitized patients","volume":"133","author":"Levy","year":"2014","journal-title":"Journal of Allergy and Clinical Immunology"},{"key":"2025082708083170000_13.1.e232844.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2006.01193.x"},{"key":"2025082708083170000_13.1.e232844.3","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1111\/cea.12261","article-title":"Goat's milk allergy without cow's milk allergy: suppression of non-cross-reactive epitopes on caprine \u03b2-casein","volume":"44","author":"Hazebrouck","year":"2014","journal-title":"Clin Exp Allergy"},{"key":"2025082708083170000_13.1.e232844.4","first-page":"39","article-title":"Selective allergy to sheep's and goat's milk proteins","volume":"32","author":"Mu\u00f1oz Mart\u00edn","year":"2004","journal-title":"Allergol Immunopathol"},{"key":"2025082708083170000_13.1.e232844.5","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1157\/13106780","article-title":"Goat's milk allergy","volume":"35","author":"Tavares","year":"2007","journal-title":"Allergol Immunopathol"},{"key":"2025082708083170000_13.1.e232844.6","doi-asserted-by":"crossref","unstructured":"Cabanillas Platero M , Pi\u00f1ero Saavedra M , Goat PSM . 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