{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:05:42Z","timestamp":1756339542780,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,3,4]]},"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:p>Actinomycosis is an uncommon, chronic suppurative granulomatous infection and needs to be considered as a differential diagnosis. A 56-year-old woman with a background of type 2 diabetes mellitus and breast carcinoma was referred to the Oral and Maxillofacial Surgery 2-week wait clinic, regarding a tender sublingual mass and firm erythematous swelling in the right submandibular and submental region. This was slowly progressive and had not responded to oral co-amoxiclav. An orthopantomogram showed a well-defined radiolucency and smaller radiolucent lesions throughout the edentulous right body of the mandible. A contrast-enhanced CT confirmed a right submandibular abscess communicating with cavitating lesions. The differentials included osteomyelitis, bony metastases, multiple myeloma or other cystic lesions. The patient underwent incision and drainage of the abscess, alongside biopsies, and intravenous co-amoxiclav was given. Microbiology cultures confirmed the presence of <jats:italic>Actinomyces israelii<\/jats:italic> and a diagnosis of cervicofacial actinomycosis with mandibular osteomyelitis. The patient was successfully treated with prolonged antibiotics.<\/jats:p>","DOI":"10.1136\/bcr-2019-232850","type":"journal-article","created":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T05:50:50Z","timestamp":1586238650000},"page":"e232850","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Bony cystic lesion with associated submandibular lymphadenopathy on a background of breast carcinoma: an unexpected case of cervicofacial actinomycosis"],"prefix":"10.1136","volume":"13","author":[{"given":"Lwazi","family":"Sibanda","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Worcestershire Acute Hospitals NHS Trust, Worcester, Worcestershire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5531-1891","authenticated-orcid":false,"given":"Emma","family":"Wates","sequence":"additional","affiliation":[{"name":"University of Bristol Medical School, Bristol, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6913-1557","authenticated-orcid":false,"given":"James","family":"Higginson","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Queen Elizabeth Hospital Birmingham, Edgbaston, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,4,6]]},"reference":[{"key":"2025082709420221000_13.4.e232850.1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(97)90313-9"},{"key":"2025082709420221000_13.4.e232850.2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d6099"},{"key":"2025082709420221000_13.4.e232850.3","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.radcr.2017.10.018","article-title":"Craniofacial Actinomyces osteomyelitis evolving from sinusitis","volume":"13","author":"Shen","year":"2018","journal-title":"Radiol Case Rep"},{"key":"2025082709420221000_13.4.e232850.4","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199905)21:3<264::AID-HED12>3.0.CO;2-Y"},{"key":"2025082709420221000_13.4.e232850.5","first-page":"116","article-title":"Cervicofacial actinomycosis: still a difficult differential diagnosis","volume":"25","author":"Volante","year":"2005","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"2025082709420221000_13.4.e232850.6","doi-asserted-by":"crossref","first-page":"e627","DOI":"10.4317\/medoral.19124","article-title":"Treatment of cervicofacial actinomycosis: a report of 19 cases and review of literature","volume":"18","author":"Moghimi","year":"2013","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"2025082709420221000_13.4.e232850.7","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-005-0030-0"},{"key":"2025082709420221000_13.4.e232850.8","first-page":"331","article-title":"Cervicofacial actinomycosis: CT and MR imaging findings in seven patients","volume":"24","author":"Park","year":"2003","journal-title":"AJNR Am J Neuroradiol"},{"key":"2025082709420221000_13.4.e232850.9","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-008733"},{"key":"2025082709420221000_13.4.e232850.10","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S39601"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-232850","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:42:07Z","timestamp":1756312927000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-232850"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":10,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,4,6]]},"published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1136\/bcr-2019-232850"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-232850","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2020,4]]}}}