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Investigations later revealed a positive titre of voltage-gated potassium channel (VGKC) antibodies, subtype leucine-rich glioma inactivated 1 accounting for his symptoms which dramatically resolved with steroids and immunoglobulins. This case highlighted the need for maintaining broad differential diagnoses in a patient presenting with unusual psychiatric symptoms.<\/jats:p>","DOI":"10.1136\/bcr-2019-233179","type":"journal-article","created":{"date-parts":[[2020,12,13]],"date-time":"2020-12-13T23:30:10Z","timestamp":1607902210000},"page":"e233179","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Voltage-gated potassium channel limbic encephalitis presenting as functional cognitive impairment"],"prefix":"10.1136","volume":"13","author":[{"given":"Eric","family":"Garrels","sequence":"first","affiliation":[{"name":"Psychiatric Liaison Service (Queen's Hospital), NELFT NHS Foundation Trust, Romford, Essex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fawziya","family":"Huq","sequence":"additional","affiliation":[{"name":"Psychiatric Liaison Service (Queen's Hospital), NELFT NHS Foundation Trust, Romford, Essex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gavin","family":"McKay","sequence":"additional","affiliation":[{"name":"Psychiatric Liaison Service (Queen's Hospital), NELFT NHS Foundation Trust, Romford, Essex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,12,13]]},"reference":[{"key":"2025082623485451000_13.12.e233179.1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1038\/ncpneuro0033","article-title":"Autoimmune channelopathies","volume":"1","author":"Buckley","year":"2005","journal-title":"Nat Clin Pract Neurol"},{"key":"2025082623485451000_13.12.e233179.2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.7.1481"},{"key":"2025082623485451000_13.12.e233179.3","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0b013e31813e34a5"},{"key":"2025082623485451000_13.12.e233179.4","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq213"},{"key":"2025082623485451000_13.12.e233179.5","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.105.012864"},{"key":"2025082623485451000_13.12.e233179.6","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.23.4.jnp425"},{"key":"2025082623485451000_13.12.e233179.7","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2017-315720"},{"key":"2025082623485451000_13.12.e233179.8","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)00401-9"},{"key":"2025082623485451000_13.12.e233179.9","doi-asserted-by":"publisher","DOI":"10.1176\/appi.neuropsych.17120343"},{"key":"2025082623485451000_13.12.e233179.10","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181d3e404"},{"key":"2025082623485451000_13.12.e233179.11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fpsyt.2017.00025","article-title":"Red flags: clinical signs for identifying autoimmune encephalitis in psychiatric patients","volume":"8","author":"Herken","year":"2017","journal-title":"Front Psychiatry"},{"key":"2025082623485451000_13.12.e233179.12","doi-asserted-by":"crossref","unstructured":"Affan M , Madani S , Osman G , et al . Clinical presentation and treatment of autoimmune encephalitis: single center cohort study of 47 cases. 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