{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T13:55:00Z","timestamp":1768485300548,"version":"3.49.0"},"reference-count":9,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,2,8]]},"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:p>We present a case of a 72-year-old women who presented with a persistent sore throat and productive cough. On flexible nasendoscopy examination, she was found to have a fairly superficial ulcer affecting the laryngeal surface and tip of her epiglottis. On her second microlaryngoscopy and biopsy, direct immunofluorescent staining of the biopsy was analysed and the histological findings were in keeping with a diagnosis of mucous membrane pemphigoid (MMP). MMP is a rare chronic autoimmune condition characterised by the presence of blistering subepithelial lesions that can cause scarring. Laryngeal MMP affects only 1 in 10\u2009million people and can lead to life-threatening airway compromise arising from scarring and stenosis. As there is a large spectrum of disease, it is important to adopt a multidisciplinary approach including dermatologists, otolaryngologists and ophthalmologists for prompt diagnosis and early recognition of potential complications, maximising functional outcomes for patients.<\/jats:p>","DOI":"10.1136\/bcr-2019-233566","type":"journal-article","created":{"date-parts":[[2020,2,26]],"date-time":"2020-02-26T04:29:29Z","timestamp":1582691369000},"page":"e233566","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Persistent sore throat: a case of laryngeal mucous membrane pemphigoid"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5276-8802","authenticated-orcid":false,"given":"Sarah","family":"Law","sequence":"first","affiliation":[{"name":"Otolaryngology, Musgrove Park Hospital, Taunton, Somerset, UK"},{"name":"Health and Social Sciences, University of Bristol, Bristol, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeni","family":"Pillai","sequence":"additional","affiliation":[{"name":"Otolaryngology, Musgrove Park Hospital, Taunton, Somerset, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Burgess","sequence":"additional","affiliation":[{"name":"Otolaryngology, Musgrove Park Hospital, Taunton, Somerset, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,2,25]]},"reference":[{"key":"2025082802035371000_13.2.e233566.1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20763"},{"key":"2025082802035371000_13.2.e233566.2","doi-asserted-by":"crossref","DOI":"10.1001\/archderm.138.3.370","article-title":"The first international consensus on mucous membrane pemphigoid","volume":"138","author":"Chan","year":"2002","journal-title":"Arch Dermatol"},{"key":"2025082802035371000_13.2.e233566.3","first-page":"E617","article-title":"Scarring mucous membrane pemphigoid presenting as double stenosis of the larynx and esophagus: precautions during therapy can avoid complications","volume":"46 Suppl 1 UCTN","author":"Schempf","year":"2014","journal-title":"Endoscopy"},{"key":"2025082802035371000_13.2.e233566.4","doi-asserted-by":"publisher","DOI":"10.1177\/000348940311200314"},{"key":"2025082802035371000_13.2.e233566.5","doi-asserted-by":"publisher","DOI":"10.1097\/01.md.0000231954.08350.52"},{"key":"2025082802035371000_13.2.e233566.6","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2017-220887","article-title":"Paraneoplastic mucous membrane pemphigoid with ocular and laryngeal involvement","volume":"57","author":"Lambiel","year":"2017","journal-title":"BMJ Case Rep"},{"key":"2025082802035371000_13.2.e233566.7","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1111\/coa.12676","article-title":"Assessment and management of laryngeal mucous membrane pemphigoid: our experience in six patients and a proposed severity scale","volume":"42","author":"Nash","year":"2017","journal-title":"Clin Otolaryngol"},{"key":"2025082802035371000_13.2.e233566.8","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1177\/014556139607501007","article-title":"Cicatricial pemphigoid of the larynx: a case report of surgical treatment","volume":"75","author":"el-Sayed","year":"1996","journal-title":"Ear Nose Throat J"},{"key":"2025082802035371000_13.2.e233566.9","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jvoice.2017.03.025","article-title":"Epiglottitis as the presenting sign of mucous membranous pemphigoid: a case report","volume":"32","author":"Carmel-Neiderman","year":"2018","journal-title":"J Voice"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-233566","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:04:02Z","timestamp":1756371842000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-233566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":9,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,2,25]]},"published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1136\/bcr-2019-233566"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-233566","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2]]}}}