{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T14:18:52Z","timestamp":1758637132859,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,3,3]]},"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:p>Mycobacterial infection of the salivary glands is extremely rare, even in endemic countries. Differential diagnosis with benign or malignant neoplasms is challenging, and treatment is often delayed. We describe the case of a 62-year-old female patient who presented with a 2-month-old complaint of a right preauricular painless swelling. An ultrasound-guided fine-needle aspiration biopsy was performed, with a resulting lymphocytic infiltrate, without clear atypia. MRI demonstrated a lesion with ill-defined contours, described as probably malignant. Because of this mismatch in results, a core biopsy of the main lesion was performed, demonstrating granulomas with central necrosis, with no mycobacteria detected in PCR or culture. As the lesion continued to enlarge, a new biopsy was ordered, and this time <jats:italic>Mycobacterium tuberculosis<\/jats:italic> was detected. Treatment with extrapulmonary tuberculosis therapy was initiated. The sensitivity of PCR and culture combined is only 73% in extrapulmonary tuberculosis. A systematic approach may prevent unnecessary surgical interventions.<\/jats:p>","DOI":"10.1136\/bcr-2019-233616","type":"journal-article","created":{"date-parts":[[2020,8,19]],"date-time":"2020-08-19T02:46:23Z","timestamp":1597805183000},"page":"e233616","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Tuberculosis as a differential diagnosis of salivary gland malignancy"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3127-9406","authenticated-orcid":false,"given":"Nuno","family":"Medeiros","sequence":"first","affiliation":[{"name":"Otolaryngology, Centro Hospitalar de Vila Nova de Gaia Espinho, EPE, Vila Nova de Gaia, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Otolaryngology, Centro Hospitalar de Vila Nova de Gaia Espinho, EPE, Vila Nova de Gaia, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o","family":"Larangeiro","sequence":"additional","affiliation":[{"name":"Otolaryngology, Centro Hospitalar de Vila Nova de Gaia Espinho, EPE, Vila Nova de Gaia, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artur","family":"Cond\u00e9","sequence":"additional","affiliation":[{"name":"Otolaryngology, Centro Hospitalar de Vila Nova de Gaia Espinho, EPE, Vila Nova de Gaia, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,8,18]]},"reference":[{"key":"2025082701165866000_13.8.e233616.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2015.05.017"},{"key":"2025082701165866000_13.8.e233616.2","doi-asserted-by":"publisher","DOI":"10.1177\/000348940511400710"},{"key":"2025082701165866000_13.8.e233616.3","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2001.123923"},{"key":"2025082701165866000_13.8.e233616.4","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1258\/0022215011907073","article-title":"Tuberculous parotitis: a series of five cases diagnosed on fine needle aspiration cytology","volume":"115","author":"Handa","year":"2001","journal-title":"J Laryngol Otol"},{"key":"2025082701165866000_13.8.e233616.5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.4103\/0975-5950.111381","article-title":"Tuberculosis of parotid gland masquerading parotid neoplasm","volume":"3","author":"Vyas","year":"2012","journal-title":"Natl J Maxillofac Surg"},{"key":"2025082701165866000_13.8.e233616.6","first-page":"67","article-title":"Tuberculosis of the parotid gland","volume":"45","author":"Janmeja","year":"2003","journal-title":"Indian J Chest Dis Allied Sci"},{"key":"2025082701165866000_13.8.e233616.7","doi-asserted-by":"crossref","unstructured":"Cata\u00f1o JC , Robledo J . Tuberculous Lymphadenitis and Parotitis. In: Schlossberg D , ed. Tuberculous and nontuberculous mycobacterial infections. 7th edn. Philadelphia, 2017: 343\u201354.","DOI":"10.1128\/9781555819866.ch21"},{"key":"2025082701165866000_13.8.e233616.8","doi-asserted-by":"crossref","first-page":"318","DOI":"10.4103\/ijmy.ijmy_86_17","article-title":"Parotid gland tuberculosis","volume":"6","author":"Dixit","year":"2017","journal-title":"Int J Mycobacteriol"},{"key":"2025082701165866000_13.8.e233616.9","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1258\/0022215054020494","article-title":"Tuberculosis of the parotid gland","volume":"119","author":"Iser\u00ec","year":"2005","journal-title":"J Laryngol Otol"},{"key":"2025082701165866000_13.8.e233616.10","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.53.5.355"},{"key":"2025082701165866000_13.8.e233616.11","unstructured":"WHO . Guidelines for treatment of drug-susceptible tuberculosis and patient care 2017."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-233616","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T08:17:08Z","timestamp":1756282628000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-233616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":11,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2020,8,18]]},"published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1136\/bcr-2019-233616"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-233616","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2020,8]]}}}