{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:02:31Z","timestamp":1756425751158,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,3,23]]},"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:p>Meningioma, the second most common primary tumour of the central nervous system, is classified into three different grades based on their characteristics. Each tumour grade includes different molecular subtype, growth potential, and thus, different prognosis. Grade I meningioma is the most common subtype with a benign course, in which systemic dissemination rarely occurs. We present the case of a 48-year-old male patient with a history of grade I meningioma who was referred 3 years after the initial diagnosis to our centre due to pelvic pain. Computed tomography (CT) images showed new pelvic bone lesions whose histopathological report was compatible with a grade I meningioma. Neither hormonal therapy concomitant with octreotide nor hydroxiurea treatments were effective. Very little is known about this entity\u2019s prevalence and treatment when disseminated disease occurs. Thus, we think it is important to increase the positive and negative clinical experiences in this setting.<\/jats:p>","DOI":"10.1136\/bcr-2019-233708","type":"journal-article","created":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T05:55:10Z","timestamp":1586238910000},"page":"e233708","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Grade I meningioma with disseminated bone disease: a rare clinical phenomenon"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8492-5195","authenticated-orcid":false,"given":"Oriol","family":"Mirallas","sequence":"first","affiliation":[{"name":"Medical Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Marmolejo","sequence":"additional","affiliation":[{"name":"Medical Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Augusto","family":"Valdivia","sequence":"additional","affiliation":[{"name":"Medical Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Vieito","sequence":"additional","affiliation":[{"name":"Medical Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,4,6]]},"reference":[{"key":"2025082723165555000_13.4.e233708.1","first-page":"1","article-title":"Meningioma metastases: incidence and proposed screening paradigm","author":"Dalle Ore","year":"2019","journal-title":"J 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