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Biopsy demonstrated an outstanding reduction in eosinophilic infiltration and re-epithelisation of nasal mucosa with normal features after reboot approach compared with previous surgeries. Therefore, reboot approach may become an effective instrument in plurioperated patients with CRSwNP who suffer from a nasal condition that is recalcitrant to pharmacological therapies and is unsatisfactorily treated by standard surgical techniques.<\/jats:p>","DOI":"10.1136\/bcr-2019-233726","type":"journal-article","created":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T05:39:25Z","timestamp":1585892365000},"page":"e233726","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Long-lasting clinical, radiological and immunological remission of severe nasal polyposis by means of \u2018reboot\u2019 surgery"],"prefix":"10.1136","volume":"13","author":[{"given":"Luca","family":"Malvezzi","sequence":"first","affiliation":[{"name":"Otorhinolaryngology, Humanitas Clinical and Research Center, Rozzano, MI, 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