{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:48:48Z","timestamp":1778546928833,"version":"3.51.4"},"reference-count":16,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,3,13]]},"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:p>A one-eyed 67-year-old man with 20\/400 vision, dense cataract, previously failed trabeculectomy and medically uncontrolled advanced glaucoma underwent a single-site phacoemulsification with repeat trabeculectomy and mitomycin C. One-week postoperatively, vision in the right eye improved to 20\/120, good bleb and intraocular pressure (IOP) of 14\u2009mm Hg. By third postoperative week, patient presented to the emergency with diminished vision, pain and redness in right eye of 2 days duration and was diagnosed to have bleb-related endophthalmitis (BRE). Vitreous biopsy, smear from the bleb were taken and underwent pars plana vitrectomy with intraocular antibiotic injection. Smears and cultures were negative however, aqueous DNA-PCR was positive for <jats:italic>Mycobacterium tuberculosis<\/jats:italic>. Revisited history revealed treated pulmonary tuberculosis 3 years ago with a positive Mantoux test (17\u2009mm) and hilar prominence on chest X-ray. One month after starting anti-tubercular therapy (ATT), the BRE resolved and vision improved to 20\/60 with IOP of 14\u2009mm Hg and the ATT was continued.<\/jats:p>","DOI":"10.1136\/bcr-2019-234175","type":"journal-article","created":{"date-parts":[[2020,3,24]],"date-time":"2020-03-24T15:35:32Z","timestamp":1585064132000},"page":"e234175","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Bleb-related tuberculous endophthalmitis following combined phacoemulsification and trabeculectomy with mitomycin C"],"prefix":"10.1136","volume":"13","author":[{"given":"Praveen Kumar","family":"Seth","sequence":"first","affiliation":[{"name":"Glaucoma, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Savitri","family":"Sharma","sequence":"additional","affiliation":[{"name":"Jhaveri Microbiology Centre, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sirisha","family":"Senthil","sequence":"additional","affiliation":[{"name":"Glaucoma, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,3,24]]},"reference":[{"key":"2025082801553966000_13.3.e234175.1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1978.03910050541009"},{"key":"2025082801553966000_13.3.e234175.2","doi-asserted-by":"publisher","DOI":"10.3129\/i09-050"},{"key":"2025082801553966000_13.3.e234175.3","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/S0161-6420(97)30196-1","article-title":"Blebitis, early endophthalmitis, and late endophthalmitis after glaucoma-filtering surgery","volume":"104","author":"Ciulla","year":"1997","journal-title":"Ophthalmology"},{"key":"2025082801553966000_13.3.e234175.4","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1055\/s-2008-1055146","article-title":"Endophthalmitis caused by Mycobacterium tuberculosis. Metastatische endophthalmitis durch Mycobacterium tuberculosis","volume":"6","author":"Manthey","year":"1982","journal-title":"Klin Monotsbl Augenheilkd"},{"key":"2025082801553966000_13.3.e234175.5","doi-asserted-by":"crossref","DOI":"10.1186\/s12348-015-0046-z","article-title":"A case of tuberculous endophthalmitis successfully treated with vitrectomy followed by antituberculous agents","volume":"5","author":"Hase","year":"2015","journal-title":"J Ophthalmic Inflamm Infect"},{"key":"2025082801553966000_13.3.e234175.6","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1590\/S0037-86822000000300003","article-title":"Nested-Pcr using mpb64 fragment improves the diagnosis of pleural and meningeal tuberculosis","volume":"33","author":"Martins","year":"2000","journal-title":"Rev Soc Bras Med Trop"},{"key":"2025082801553966000_13.3.e234175.7","article-title":"Trends in tuberculosis--United States, 2004","volume":"54","year":"2005","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2025082801553966000_13.3.e234175.8","first-page":"90","article-title":"Who are the patients with extrapulmonary tuberculosis?","volume":"21","author":"Sanches","year":"2015","journal-title":"Rev Port Pneumol"},{"key":"2025082801553966000_13.3.e234175.9","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(67)92860-7"},{"key":"2025082801553966000_13.3.e234175.10","doi-asserted-by":"publisher","DOI":"10.1076\/opep.9.4.239.1507"},{"key":"2025082801553966000_13.3.e234175.11","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/IIO.0b013e318074de79","article-title":"Diagnosis of ocular tuberculosis: a role for new testing modalities?","volume":"47","author":"Bramante","year":"2007","journal-title":"Int Ophthalmol Clin"},{"key":"2025082801553966000_13.3.e234175.12","doi-asserted-by":"publisher","DOI":"10.1097\/00061198-200012000-00004"},{"key":"2025082801553966000_13.3.e234175.13","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.2147\/OPTH.S65254","article-title":"Ocular tuberculosis: current perspectives","volume":"9","author":"Shakarchi","year":"2015","journal-title":"Clin Ophthalmol"},{"key":"2025082801553966000_13.3.e234175.14","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2010.235"},{"key":"2025082801553966000_13.3.e234175.15","doi-asserted-by":"crossref","unstructured":"Dinnes J , Deeks J , Kunst H , et al . A systematic review of rapid diagnostic tests for the detection of tuberculosis infection. In: NIHR health technology assessment programme: executive summaries. 11. NIHR Journals Library, 2007.doi:10.3310\/hta11030","DOI":"10.3310\/hta11030"},{"key":"2025082801553966000_13.3.e234175.16","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1080\/09273948.2016.1178304","article-title":"Diagnosis of ocular tuberculosis","volume":"26","author":"Ang","year":"2018","journal-title":"Ocul Immunol Inflamm"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-234175","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:55:50Z","timestamp":1756371350000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-234175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":16,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020,3,24]]},"published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1136\/bcr-2019-234175"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-234175","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3]]}}}