{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T23:39:54Z","timestamp":1775777994885,"version":"3.50.1"},"reference-count":7,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,9,6]]},"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>An 18-year-old man presented with fever, night sweats and progressive weight loss over 2\u2009months. He had a history of Peutz-Jeghers syndrome (PJS) complicated by previous intussusception requiring left hemicolectomy. Colonoscopy revealed deep punched out ulceration throughout the colon with multiple polyps. He was investigated for tuberculosis based on his occupation as dairy farmer. Following a negative QuantiFERON test, he was started on infliximab as emergency therapy and made a good recovery at 6 months follow-up. We describe a case of newly diagnosed Crohn\u2019s disease (CD) in an adolescent with a background diagnosis of PJS. While inflammatory bowel disease, such as CD, is common in the UK, the association with PJS is very rare, with only two existing case reports in the literature.<\/jats:p>","DOI":"10.1136\/bcr-2020-234513","type":"journal-article","created":{"date-parts":[[2020,10,4]],"date-time":"2020-10-04T17:15:10Z","timestamp":1601831710000},"page":"e234513","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Interesting case of dual pathology: Crohn\u2019s disease and Peutz-Jeghers syndrome"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1091-5808","authenticated-orcid":false,"given":"Mantej","family":"Sehmbhi","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, London North West University Healthcare NHS Trust, London, UK"},{"name":"School of Public Health, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Penelope","family":"Sellers","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, London North West University Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9668-0316","authenticated-orcid":false,"given":"Jonathan","family":"Segal","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, London North West University Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Clark","sequence":"additional","affiliation":[{"name":"The Polyposis Registry, St Mark\u2019s Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,10,4]]},"reference":[{"key":"2025082706564269000_13.10.e234513.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32448-0"},{"key":"2025082706564269000_13.10.e234513.2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.198499"},{"key":"2025082706564269000_13.10.e234513.3","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.725"},{"key":"2025082706564269000_13.10.e234513.4","first-page":"670","article-title":"[Familial occurrence of Peutz-Jeghers syndrome and Crohn disease with manifestation of both diseases in the same patient]","volume":"23","author":"Posselt","year":"1985","journal-title":"Z Gastroenterol"},{"key":"2025082706564269000_13.10.e234513.5","doi-asserted-by":"crossref","first-page":"243","DOI":"10.4166\/kjg.2013.62.4.243","article-title":"[A case of Crohn's disease accompanied by Peutz-Jeghers syndrome]","volume":"62","author":"Um","year":"2013","journal-title":"Korean J Gastroenterol"},{"key":"2025082706564269000_13.10.e234513.6","doi-asserted-by":"publisher","DOI":"10.1007\/s10689-011-9442-1"},{"key":"2025082706564269000_13.10.e234513.7","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1016\/j.cgh.2019.10.035","article-title":"Positioning therapies in the management of Crohn's disease","volume":"18","author":"Nguyen","year":"2020","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-234513","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T13:56:48Z","timestamp":1756303008000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-234513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":7,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2020,10,4]]},"published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1136\/bcr-2020-234513"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-234513","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10]]}}}