{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:03:04Z","timestamp":1756425784799,"version":"3.44.0"},"reference-count":16,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,5,17]]},"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:p>Macroscopic fat inside an adrenal lesion on CT is pathognomonic for myelolipoma, a benign neoplasm. Without macroscopic fat, it can be difficult to discern the nature of an indeterminate adrenal mass on imaging. One possible diagnosis for an indeterminate lesion without macroscopic fat is an adrenal oncocytic neoplasm (AON). Despite its typical benign presentation cases of malignant AON have been reported. Patients with malignant AON are often not surgical candidates and survival for unresected disease is 20%\u201335%. We present the third report of an AON of uncertain malignant potential (AONUMP) associated with a macroscopic fatty component with the largest reported size and longest duration of follow-up in the literature. This report details diagnostic and therapeutic challenges posed by AONUMP. This case highlights how pathognomonic radiographical findings associated with benign myelolipoma might mask rare, potentially malignant, lipomatous tumours.<\/jats:p>","DOI":"10.1136\/bcr-2020-234591","type":"journal-article","created":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T05:55:23Z","timestamp":1591941323000},"page":"e234591","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Adrenocortical neoplasm of uncertain malignant potential with a myelolipomatous component"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7912-8896","authenticated-orcid":false,"given":"Adithya","family":"Balasubramanian","sequence":"first","affiliation":[{"name":"Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Scovell","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam E","family":"Dowell","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine, Houston, Texas, USA"},{"name":"Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wesley","family":"Mayer","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine, Houston, Texas, USA"},{"name":"Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,6,11]]},"reference":[{"key":"2025082801120698000_13.6.e234591.1","first-page":"E334","article-title":"Adrenal oncocytic neoplasm with uncertain malignant potential","volume":"13","author":"Ahmed","year":"2013","journal-title":"Sultan Qaboos Univ Med J"},{"key":"2025082801120698000_13.6.e234591.2","doi-asserted-by":"publisher","DOI":"10.1159\/000345141"},{"key":"2025082801120698000_13.6.e234591.3","doi-asserted-by":"publisher","DOI":"10.1177\/106689690401200304"},{"key":"2025082801120698000_13.6.e234591.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2009.03.010"},{"key":"2025082801120698000_13.6.e234591.5","doi-asserted-by":"publisher","DOI":"10.1530\/ERC-16-0564"},{"key":"2025082801120698000_13.6.e234591.6","doi-asserted-by":"publisher","DOI":"10.4158\/EP.15.2.128"},{"key":"2025082801120698000_13.6.e234591.7","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s12149-013-0764-y","article-title":"Recurrence of a functional adrenocortical oncocytoma of borderline malignant potential showing high FDG uptake on 18F-FDG PET\/CT","volume":"28","author":"Son","year":"2014","journal-title":"Ann Nucl Med"},{"key":"2025082801120698000_13.6.e234591.8","doi-asserted-by":"publisher","DOI":"10.1159\/000330997"},{"key":"2025082801120698000_13.6.e234591.9","doi-asserted-by":"crossref","DOI":"10.1186\/1752-1947-2-228","article-title":"Adrenocortical oncocytic neoplasm presenting with Cushing's syndrome: a case report","volume":"2","author":"Kabayegit","year":"2008","journal-title":"J Med Case Rep"},{"key":"2025082801120698000_13.6.e234591.10","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.ejro.2017.08.002","article-title":"Patient-Specific workup of adrenal incidentalomas","volume":"4","author":"Haan de","year":"2017","journal-title":"Eur J Radiol Open"},{"key":"2025082801120698000_13.6.e234591.11","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-2639"},{"key":"2025082801120698000_13.6.e234591.12","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/s00428-015-1732-9","article-title":"Immunohistochemical distinction of metastases of renal cell carcinoma to the adrenal from primary adrenal nodules, including oncocytic tumor","volume":"466","author":"Li","year":"2015","journal-title":"Virchows Arch"},{"key":"2025082801120698000_13.6.e234591.13","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPCDZLC13RSXRZ"},{"key":"2025082801120698000_13.6.e234591.14","doi-asserted-by":"crossref","DOI":"10.1186\/1746-1596-5-51","article-title":"Adrenocortical carcinosarcoma: a case report and review of the literature","volume":"5","author":"Sasaki","year":"2010","journal-title":"Diagn Pathol"},{"key":"2025082801120698000_13.6.e234591.15","first-page":"260","article-title":"Adrenal cortical carcinoma with adenosquamous differentiation. 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