{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T23:05:13Z","timestamp":1781910313332,"version":"3.54.5"},"reference-count":11,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,7,22]]},"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:p>Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune neuropathy characterised by insidious onset, progressive course, proximal and distal symmetrical weakness, and sensory impairment. It may affect patients of any age with varying degrees of clinical involvement and response rates to existing treatments. Sj\u00f6gren syndrome (SS) is a systemic autoimmune disorder that primarily affects the exocrine glands causing a sicca syndrome. It may affect the peripheral nervous system, usually causing painful small fibre or pure sensory axonal neuropathy, ganglioneuronopathy or a predominantly sensory CIDP. We report the case of a 71-year-old man diagnosed with a debilitating and difficult-to-treat CIDP who, 5 years later, developed SS with pulmonary involvement. Due to lack of response to treatments other than periodic intravenous immunoglobulin (IVIg) every 12 days, we started adjuvant treatment with rituximab which increased the time interval between IVIg therapies by 50%, providing better quality of life for the patient.<\/jats:p>","DOI":"10.1136\/bcr-2020-234681","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T02:30:47Z","timestamp":1598495447000},"page":"e234681","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Adjuvant rituximab improves sensory ataxia in CIDP-related Sj\u00f6gren syndrome"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8610-8925","authenticated-orcid":false,"given":"Raquel","family":"Rocha","sequence":"first","affiliation":[{"name":"Neurology, Hospital Pedro Hispano, Unidade Local de Sa\u00fade de Matosinhos, Matosinhos, Portugal"},{"name":"Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filipe","family":"Correia","sequence":"additional","affiliation":[{"name":"Neurology, Hospital Pedro Hispano, Unidade Local de Sa\u00fade de Matosinhos, Matosinhos, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreia","family":"Santos","sequence":"additional","affiliation":[{"name":"Neurology, Hospital Pedro Hispano, Unidade Local de Sa\u00fade de Matosinhos, Matosinhos, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Martins","sequence":"additional","affiliation":[{"name":"Neurology, Hospital Pedro Hispano, Unidade Local de Sa\u00fade de Matosinhos, Matosinhos, Portugal"},{"name":"MedicilLisboa, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,8,26]]},"reference":[{"key":"2025082713083560000_13.8.e234681.1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2014-309697"},{"key":"2025082713083560000_13.8.e234681.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02930.x"},{"key":"2025082713083560000_13.8.e234681.3","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00295"},{"key":"2025082713083560000_13.8.e234681.4","doi-asserted-by":"publisher","DOI":"10.1177\/1756285611405564"},{"key":"2025082713083560000_13.8.e234681.5","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-207499"},{"key":"2025082713083560000_13.8.e234681.6","first-page":"35","article-title":"2016 Classification Criteria for primary Sj\u00f6gren\u2019s Syndrome: A Consensus and Data-Driven Methodology Involving Three International Patient Cohorts.","volume":"69","author":"Shiboski","year":"2016","journal-title":"Accept Publ Ann Rheum Dis Arthritis Rheum"},{"key":"2025082713083560000_13.8.e234681.7","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2016-000279"},{"key":"2025082713083560000_13.8.e234681.8","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.jbspin.2014.04.002","article-title":"Is there specific neurological disorders of primary Sj\u00f6gren's syndrome?","volume":"82","author":"Carvajal Alegria","year":"2015","journal-title":"Joint Bone Spine"},{"key":"2025082713083560000_13.8.e234681.9","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(82)90648-5"},{"key":"2025082713083560000_13.8.e234681.10","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2019-216114"},{"key":"2025082713083560000_13.8.e234681.11","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/jns.12287","article-title":"Rituximab in chronic inflammatory demyelinating polyradiculoneuropathy with associated diseases","volume":"23","author":"Roux","year":"2018","journal-title":"J Peripher Nerv Syst"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-234681","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:08:42Z","timestamp":1756325322000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-234681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":11,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2020,8,26]]},"published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1136\/bcr-2020-234681"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-234681","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8]]}}}