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Further work-up showed vasculitic involvement of the coeliac, superior mesenteric and femoral arteries with heavy collateralisation. These findings were most consistent with widespread Takayasu arteritis that had been untreated for nearly 20 years. It was necessary to define the degree of active inflammation and need for immediate therapy, as the patient had a concomitant latent tuberculosis infection that precluded the use of immunosuppressive medications. This report illustrates an unusual case of Takayasu arteritis and highlights the presentation, diagnosis and work-up of suspected cases.<\/jats:p>","DOI":"10.1136\/bcr-2020-234825","type":"journal-article","created":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T03:20:13Z","timestamp":1598325613000},"page":"e234825","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Untreated Takayasu arteritis: an unusual case of widespread disease"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2134-5158","authenticated-orcid":false,"given":"Thomas J","family":"Breen","sequence":"first","affiliation":[{"name":"Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas G","family":"Osborn","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Mayo Clinic, Rochester, Minnesota, 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