{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T07:16:56Z","timestamp":1763018216331,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,6,23]]},"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:p>Cardiac papillary fibroelastoma is a benign neoplasm that arises in the endocardium. It commonly presents as an incidental finding on transthoracic echocardiography or as emboli to the coronary, cerebral or pulmonary vasculature. Clinical manifestations described in the literature have generally been related to a sequelae of the associated embolic phenomenon of these lesions. Valve regurgitation is less common with papillary fibroelastoma and when found, it is not known to cause severe regurgitation requiring valve replacement. We report a case of papillary fibroelastoma in a patient with severe mitral and aortic valve regurgitation in association with mobile masses requiring double valve replacement. This patient managed initially as infective endocarditis with severe double valve regurgitation, was found to have valvular masses concernng for papillary fibroelastoma and subsequently confirmed on pathology.<\/jats:p>","DOI":"10.1136\/bcr-2020-234828","type":"journal-article","created":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T02:28:46Z","timestamp":1594952926000},"page":"e234828","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Double valve involvement: papillary fibroelastoma in a patient with severe mitral and aortic valve regurgitation"],"prefix":"10.1136","volume":"13","author":[{"given":"Oyintayo","family":"Ajiboye","sequence":"first","affiliation":[{"name":"Medicine, John H Stroger, Jr Hospital of Cook County, Chicago, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Michael","family":"Racoma","sequence":"additional","affiliation":[{"name":"Medicine, John H Stroger, Jr Hospital of Cook County, Chicago, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kifah","family":"Hussain","sequence":"additional","affiliation":[{"name":"Medicine, John H Stroger, Jr Hospital of Cook County, Chicago, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Mba","sequence":"additional","affiliation":[{"name":"Medicine, John H Stroger, Jr Hospital of Cook County, Chicago, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,7,16]]},"reference":[{"key":"2025082710031398000_13.7.e234828.1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.14797\/mdcvj.215","article-title":"Benign cardiac tumors: a review","volume":"6","author":"Bruckner","year":"2010","journal-title":"Methodist Debakey Cardiovasc J"},{"key":"2025082710031398000_13.7.e234828.2","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.repc.2018.02.011","article-title":"Cardiac papillary fibroelastoma: report of a surgical series","volume":"37","author":"Rodrigues","year":"2018","journal-title":"Rev Port Cardiol"},{"key":"2025082710031398000_13.7.e234828.3","first-page":"1","article-title":"An atypical cause of myocardial infarction: case report of an obstructing papillary fibroelastoma of the aortic valve","volume":"3","author":"Logan","year":"2019","journal-title":"Eur Heart J Case Rep"},{"key":"2025082710031398000_13.7.e234828.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.05.026"},{"key":"2025082710031398000_13.7.e234828.5","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1002\/cjp2.66","article-title":"KRAS mutation in papillary fibroelastoma: a true cardiac neoplasm?","volume":"3","author":"Wittersheim","year":"2017","journal-title":"J Pathol Clin Res"},{"key":"2025082710031398000_13.7.e234828.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(03)00249-7"},{"key":"2025082710031398000_13.7.e234828.7","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.22.2687"},{"key":"2025082710031398000_13.7.e234828.8","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1093\/ejcts\/ezy307","article-title":"Suspected endocarditis turns out to be a fibroelastoma","volume":"55","author":"Laux","year":"2019","journal-title":"Eur J Cardiothorac Surg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-234828","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:03:24Z","timestamp":1756314204000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-234828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":8,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2020,7,16]]},"published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1136\/bcr-2020-234828"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-234828","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2020,7]]}}}