{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:29:00Z","timestamp":1780964940037,"version":"3.54.1"},"reference-count":16,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,6,14]]},"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:p>Persistent Mullerian duct syndrome has been described as a disease of internal male pseudohermaphroditism, a rare autosomal recessive disease, characterised by persistent Mullerian derivatives in patients with male pattern 46, XY karyotype and normal pattern virilisation. We present a case of an elderly man, who on evaluation for bilateral undescended testes was found to have a pelvic mass suggestive of malignant transformation of an undescended testis on imaging. On surgical exploration, uterus with multiple fibroids, bilateral fallopian tubes, cervix and bilateral atrophic testes were identified. Interestingly, in this case, imaging (contrastCT and MRI) had missed Mullerian structures due to varied presentation, but exploration and excision of the structures followed by their histopathology revealed uterine leiomyomas and confirmed other Mullerian structures (bilateral fallopian tubes, cervix) with bilateral testes.<\/jats:p>","DOI":"10.1136\/bcr-2020-234890","type":"journal-article","created":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T02:40:54Z","timestamp":1594953654000},"page":"e234890","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Persistent Mullerian duct syndrome: rare presentation in an elderly man"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3294-7621","authenticated-orcid":false,"given":"Darshil Sunilbhai","family":"Shah","sequence":"first","affiliation":[{"name":"Department of Urology, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9851-6296","authenticated-orcid":false,"given":"Utsav Shailesh","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Urology, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natarajan","family":"Kumaresan","sequence":"additional","affiliation":[{"name":"Department of Urology, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,7,16]]},"reference":[{"key":"2025082713002989000_13.7.e234890.1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.10091"},{"key":"2025082713002989000_13.7.e234890.2","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/s12262-010-0003-x","article-title":"Persistent m\u00fcllerian duct syndrome: How to deal with the m\u00fcllerian duct remnants - a review","volume":"72","author":"Manjunath","year":"2010","journal-title":"Indian J Surg"},{"key":"2025082713002989000_13.7.e234890.3","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1016\/j.jpedsurg.2016.06.005","article-title":"Persistent Mullerian duct syndrome: a 24-year experience","volume":"51","author":"Saleem","year":"2016","journal-title":"J Pediatr Surg"},{"key":"2025082713002989000_13.7.e234890.4","first-page":"441","article-title":"Persistent M\u00fcllerian duct syndrome (PMDS) with testicular seminoma","volume":"44","author":"Ramanujam","year":"2001","journal-title":"Indian J Pathol Microbiol"},{"key":"2025082713002989000_13.7.e234890.5","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmi014"},{"key":"2025082713002989000_13.7.e234890.6","first-page":"735-7","article-title":"Uterine leiomyoma in a man with persistent M\u00fcllerian duct syndrome and seminoma","volume":"16","author":"Kovachev","year":"2014","journal-title":"Isr Med Assoc J"},{"key":"2025082713002989000_13.7.e234890.7","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1148\/rg.232025141","article-title":"Best cases from the AFIP","volume":"23","author":"Dekker","year":"2003","journal-title":"RadioGraphics"},{"key":"2025082713002989000_13.7.e234890.8","doi-asserted-by":"crossref","DOI":"10.4103\/0974-7796.148640","article-title":"Female form of persistent Mullerian duct syndrome: rare entity","volume":"7","author":"Solanki","year":"2015","journal-title":"Urol Ann"},{"key":"2025082713002989000_13.7.e234890.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2007.11.002"},{"key":"2025082713002989000_13.7.e234890.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(97)00104-0"},{"key":"2025082713002989000_13.7.e234890.11","doi-asserted-by":"crossref","first-page":"72","DOI":"10.4103\/0971-3026.59761","article-title":"Persistent Mullerian duct syndrome","volume":"20","author":"Renu","year":"2010","journal-title":"Indian J Radiol Imaging"},{"key":"2025082713002989000_13.7.e234890.12","first-page":"304","article-title":"Persistent Mullerian duct syndrome presenting with bilateral intra-abdominal gonadal tumours and obstructive uropathy","volume":"13","author":"Asthana","year":"2001","journal-title":"Clin Oncol"},{"key":"2025082713002989000_13.7.e234890.13","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1590\/s1677-5538.ibju.2016.0225","article-title":"Persistent Mullerian duct syndrome: a rare entity with a rare presentation in need of multidisciplinary management","volume":"42","author":"Da Aw","year":"2016","journal-title":"Int Braz J Urol"},{"key":"2025082713002989000_13.7.e234890.14","first-page":"435","article-title":"A unique case of aggressive uterine cancer in a 45-year-old man with persistent M\u00fcllerian duct syndrome","volume":"72","author":"Dimasis","year":"2019","journal-title":"Arch Esp Urol"},{"key":"2025082713002989000_13.7.e234890.15","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1080\/00015458.2006.11679852","article-title":"Persistent M\u00fcllerian duct syndrome associated with irreducible inguinal hernia, bilateral cryptorchidism and testicular neoplasia: a case report","volume":"106","author":"Yuksel","year":"2006","journal-title":"Acta Chir Belg"},{"key":"2025082713002989000_13.7.e234890.16","doi-asserted-by":"crossref","first-page":"E1084","DOI":"10.1111\/j.1464-410X.2012.11184.x","article-title":"Persistent M\u00fcllerian duct syndrome: lessons learned from managing a series of eight patients over a 10-year period and review of literature regarding malignant risk from the M\u00fcllerian remnants","volume":"110","author":"Farikullah","year":"2012","journal-title":"BJU Int"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-234890","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:00:44Z","timestamp":1756324844000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-234890"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":16,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2020,7,16]]},"published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1136\/bcr-2020-234890"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-234890","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7]]}}}