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Retrospectively, we found that the patient had vasospastic angina (VSA), a condition that has been strongly associated with the development of dobutamine-induced CS. Mechanisms of dobutamine-induced CS are not fully understood and include endothelial dysfunction leading to deficient nitric oxide-mediated coronary vasodilation in response to increased myocardial oxygen demand as well as imbalance between \u03b21 and \u03b22 adrenergic effects of dobutamine. Dobutamine-induced CS has also been much more frequently reported in patients from Asian descent with VSA. VSA should be systemically recognised in patients considered for DSE and, if present, other modalities of stress imaging should be discussed.<\/jats:p>","DOI":"10.1136\/bcr-2020-235206","type":"journal-article","created":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T16:10:20Z","timestamp":1598890220000},"page":"e235206","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Coronary artery spasm following dobutamine stress echocardiogram"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5279-5309","authenticated-orcid":false,"given":"Annick","family":"Judenherc Haouzi","sequence":"first","affiliation":[{"name":"Heart and Vascular Institute, Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefani","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Medicine, Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"Liszka","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute, Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,8,31]]},"reference":[{"key":"2025082701493707000_13.8.e235206.1","unstructured":"CDC . 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