{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T21:59:32Z","timestamp":1773352772957,"version":"3.50.1"},"reference-count":10,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,6,28]]},"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:p>Transverse vaginal septum is one of the variants of Mullerian duct anomaly, caused as a result of defective fusion or recanalisation of vaginal and Mullerian organs. At an early age, it commonly presents as primary amenorrhea along with cyclical abdominal pain while later on usually it presents as dyspareunia and infertility. Our 22-year-old patient presented with secondary amenorrhea. It is very unusual for a transverse vaginal septum to cause secondary amenorrhea. MRI and clinical examination raised the suspicion of transverse vaginal septum causing secondary amenorrhea. She attained regular menstrual cycle after septum excision. The proposed theory behind it is obliteration of microperforated transverse vaginal septum because of menstrual blood and cell debris. Thus, a rare possibility of transverse vaginal septum should also be considered as a differential diagnosis of secondary amenorrhea.<\/jats:p>","DOI":"10.1136\/bcr-2020-235374","type":"journal-article","created":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T03:20:31Z","timestamp":1598325631000},"page":"e235374","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Transverse vaginal septum presenting as secondary amenorrhoea: a rare clinical presentation"],"prefix":"10.1136","volume":"13","author":[{"given":"Garima","family":"Yadav","sequence":"first","affiliation":[{"name":"Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences, Jodhpur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neha","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences, Jodhpur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sureka","family":"Binit","sequence":"additional","affiliation":[{"name":"Department of Diagnostic & Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pratibha","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences, Jodhpur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,8,24]]},"reference":[{"key":"2025082709050987000_13.8.e235374.1","first-page":"127","article-title":"Transverse vaginal septum. A report of four cases","volume":"30","author":"Sueldo","year":"1985","journal-title":"J Reprod Med"},{"key":"2025082709050987000_13.8.e235374.2","unstructured":"Delaunay . Etude sur le cloisonnement transversal du vagin complet et incomplete d'origine congenitale. thesis, Paris 1877."},{"key":"2025082709050987000_13.8.e235374.3","doi-asserted-by":"crossref","DOI":"10.1016\/S0002-9378(16)40386-8","article-title":"Congenital vaginal occlusion of the cervix","volume":"47","author":"Dannreuther","year":"1944","journal-title":"Am J Obstet Gynecol"},{"key":"2025082709050987000_13.8.e235374.4","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.18203\/2320-1770.ijrcog20150462","article-title":"Perforated transverse vaginal septum: a rare case report","volume":"4","author":"Sasikala","year":"2015","journal-title":"Int J Reprod Contracept Obstet Gynecol"},{"key":"2025082709050987000_13.8.e235374.5","first-page":"1246","article-title":"Contributo clinico statistico sulle malformazioni della vagina osservate mella. clinica obstetrica E Ginecologica di Milano del 1906 al 1950","volume":"73","author":"Lodi","year":"1951","journal-title":"Ann Ostet Ginecol"},{"key":"2025082709050987000_13.8.e235374.6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2019\/6738380","article-title":"Application of saline infusion Sonocolpography in diagnosis and treatment of perforated transverse vaginal septum","volume":"2019","author":"Ono","year":"2019","journal-title":"Case Rep Obstet Gynecol"},{"key":"2025082709050987000_13.8.e235374.7","doi-asserted-by":"crossref","first-page":"140","DOI":"10.4274\/tjod.galenos.2019.32956","article-title":"Asymptomatic microperforated transverse vaginal septum presenting with primary infertility: a rare form of Mullerian anomaly","volume":"16","author":"Do\u011fan","year":"2019","journal-title":"Turk J Obstet Gynecol"},{"key":"2025082709050987000_13.8.e235374.8","first-page":"59","article-title":"Development of the vagina in the human fetus","volume":"24","author":"Koff","year":"1933","journal-title":"Contrib Embryol"},{"key":"2025082709050987000_13.8.e235374.9","doi-asserted-by":"crossref","first-page":"351.e5","DOI":"10.1016\/j.fertnstert.2009.12.052","article-title":"Secondary amenorrhea attributed to occlusion of microperforate transverse vaginal septum","volume":"94","author":"Nichols","year":"2010","journal-title":"Fertil Steril"},{"key":"2025082709050987000_13.8.e235374.10","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/det098"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-235374","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:05:21Z","timestamp":1756310721000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-235374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":10,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2020,8,24]]},"published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1136\/bcr-2020-235374"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-235374","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8]]}}}