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This article outlines the clinical presentation, workup and management of a 43-year-old woman who presented with a bilobed cystic mass of the right breast diagnosed as CHDC.<\/jats:p>","DOI":"10.1136\/bcr-2020-235488","type":"journal-article","created":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T12:58:15Z","timestamp":1626872295000},"page":"e235488","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Cystic hypersecretory ductal carcinoma (CHDC): a rare distinctive variant of ductal carcinoma"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6683-7300","authenticated-orcid":false,"given":"Ashley","family":"DiPasquale","sequence":"first","affiliation":[{"name":"Harvard University T H Chan School of Public Health, Boston, Massachusetts, USA"},{"name":"Department of General Surgery, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lashan","family":"Peiris","sequence":"additional","affiliation":[{"name":"Department of General Surgery, University of Alberta, Edmonton, Alberta, Canada"},{"name":"Covenant Health, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svetlana","family":"Silverman","sequence":"additional","affiliation":[{"name":"Covenant Health, Edmonton, Alberta, Canada"},{"name":"Department of Laboratory Medicine & Pathology, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,7,21]]},"reference":[{"key":"2025082712190119000_14.7.e235488.1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/00000478-198401000-00003","article-title":"Cystic hypersecretory duct carcinoma of the breast","volume":"8","author":"Rosen","year":"1984","journal-title":"Am J Surg Pathol"},{"key":"2025082712190119000_14.7.e235488.2","unstructured":"Rosen PP . 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