{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:40:16Z","timestamp":1756305616492,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,9,30]]},"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>A 61-year-old man presented to the department of clinical haematology in February 2016 with symptomatic anaemia, generalised lymphadenopathy and hepatomegaly. Routine investigations showed severe anaemia with the presence of lymphoplasmacytoid cells in the peripheral smear, and bone marrow examination with IHC and serum protein electrophoresis confirmed diagnosis of lymphoplasmacytic lymphoma. The patient received supportive transfusion therapy and combination chemotherapy. After VI cycles, the patient had a complete haematological response with marrow in remission. Maintenance rituximab was planned every 3 months for 2 years. At the time of first dose of maintenance rituximab, his haemoglobin (Hb) was 189 g\/L with low normal erythropoietin level. During the last 3 years follow-up, his Hb ranged between 16.5 and 20.1 g\/dL. All causes of secondary polycythaemia were ruled out. Workup for polycythAemia vera (PV), including JAK-2 and bone marrow, was not suggestive of PV. We labelled it as a case of polycythaemia due to undetermined aetiology.<\/jats:p>","DOI":"10.1136\/bcr-2020-235687","type":"journal-article","created":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T17:11:08Z","timestamp":1604077868000},"page":"e235687","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Polycythaemia following treatment of lymphoplasmacytic lymphoma"],"prefix":"10.1136","volume":"13","author":[{"given":"Shailendra Prasad","family":"Verma","sequence":"first","affiliation":[{"name":"Clinical Hematology, King George's Medical University, Lucknow, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhupendra","family":"Singh","sequence":"additional","affiliation":[{"name":"Clinical Hematology, King George's Medical University, Lucknow, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rashmi","family":"Kushwaha","sequence":"additional","affiliation":[{"name":"Department of Pathology, King George's Medical University, Lucknow, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Punita","family":"Pavecha","sequence":"additional","affiliation":[{"name":"Clinical Hematology, King George's Medical University, Lucknow, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,10,30]]},"reference":[{"key":"2025082707020713000_13.10.e235687.1","doi-asserted-by":"crossref","first-page":"580","DOI":"10.5858\/arpa.2012-0034-RS","article-title":"Lymphoplasmacytic lymphoma and Waldenstr\u00f6m macroglobulinemia","volume":"137","author":"Naderi","year":"2013","journal-title":"Arch Pathol Lab Med"},{"key":"2025082707020713000_13.10.e235687.2","first-page":"17","article-title":"Simultaneous occurrence of polycythemia vera and Waldenstr\u00f6m macroglobulinemia: a case report and review of the literature","volume":"32","author":"SabaNF","year":"2002","journal-title":"Haematologica(Budap)"},{"key":"2025082707020713000_13.10.e235687.3","doi-asserted-by":"crossref","first-page":"364","DOI":"10.5144\/0256-4947.2016.364","article-title":"Coexistence of chronic lymphocytic leukemia and polycythemia vera: a case report and review of the literature","volume":"36","author":"Korkmaz","year":"2016","journal-title":"Ann Saudi Med"},{"key":"2025082707020713000_13.10.e235687.4","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.3892\/ol.2015.4040","article-title":"Coexistence of follicular lymphoma and an unclassifiable myeloproliferative neoplasm in a treatment-na\u00efve patient: a case report","volume":"11","author":"Jeong","year":"2016","journal-title":"Oncol Lett"},{"key":"2025082707020713000_13.10.e235687.5","first-page":"1399","article-title":"Polycythemia vera after chemotherapy-induced remission of Hodgkin's disease: report of a case","volume":"122","author":"Quirk","year":"1980","journal-title":"Can Med Assoc J"},{"key":"2025082707020713000_13.10.e235687.6","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3343\/alm.2014.34.6.469","article-title":"A rare case of polycythemia vera following acute lymphoblastic leukemia remission","volume":"34","author":"Youk","year":"2014","journal-title":"Ann Lab Medicine"},{"key":"2025082707020713000_13.10.e235687.7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2005.05535.x"},{"key":"2025082707020713000_13.10.e235687.8","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-194908000-00005"},{"key":"2025082707020713000_13.10.e235687.9","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.25049"},{"key":"2025082707020713000_13.10.e235687.10","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2016-216686","article-title":"Polycythaemia: an unusual presentation of multiple myeloma","volume":"2016","author":"Hutchison","year":"2016","journal-title":"BMJ Case Rep"},{"key":"2025082707020713000_13.10.e235687.11","first-page":"313","article-title":"Diffuse large B-cell lymphoma and polycythemia vera discovered at the onset - a rare association and its possible importance in lymphoma prognosis","volume":"57","author":"Popov","year":"2016","journal-title":"Rom J Morphol Embryol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-235687","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:02:15Z","timestamp":1756303335000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-235687"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":11,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2020,10,30]]},"published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1136\/bcr-2020-235687"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-235687","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2020,10]]}}}