{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T10:43:33Z","timestamp":1767523413603,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,8,3]]},"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:p>Central retinal artery occlusion (CRAO) is a rare but blinding disorder. We present a case of a 81-year-old woman with multiple cardiovascular comorbidities admitted to the emergency department due to sudden, painless vision loss on left eye (oculus sinister (OS)) on awakening. The patient also reported long standing fatigue associated with effort that started 4\u2009months before admission. She presented best corrected visual acuity of counting fingers OS. Funduscopy OS revealed macular oedema with cherry red spot pattern. Blood cultures came positive for <jats:italic>Streptococcus gallolyticus<\/jats:italic> in the context of a bacteremia and native mitral valve vegetation identified on transoesophageal echocardiography. CRAO of embolic origin was admitted in the context of an infective endocarditis. CRAO can be the first manifestation of a potentially fatal systemic condition and thus multidisciplinary approach is warranted with close collaboration between ophthalmologists and internists in order to provide proper management and the best possible treatment.<\/jats:p>","DOI":"10.1136\/bcr-2020-235763","type":"journal-article","created":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T02:35:15Z","timestamp":1599100515000},"page":"e235763","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Central retinal artery occlusion from <i>Streptococcus gallolyticus<\/i> endocarditis"],"prefix":"10.1136","volume":"13","author":[{"given":"Rita","family":"Serras-Pereira","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Centro Hospitalar de Lisboa Central, EPE, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5972-4068","authenticated-orcid":false,"given":"Diogo","family":"Hipolito-Fernandes","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Centro Hospitalar de Lisboa Central, EPE, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u00edsa","family":"Azevedo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Centro Hospitalar de Lisboa Central, EPE, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u00edsa","family":"Vieira","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Centro Hospitalar de Lisboa Central, EPE, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,9,2]]},"reference":[{"key":"2025082711422409000_13.9.e235763.1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2013.25"},{"key":"2025082711422409000_13.9.e235763.2","doi-asserted-by":"crossref","first-page":"28","DOI":"10.21037\/aes.2018.05.04","article-title":"Acute retinal arterial ischemia","volume":"3","author":"Dattilo","year":"2018","journal-title":"Ann Eye Sci"},{"key":"2025082711422409000_13.9.e235763.3","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ncl.2016.08.013","article-title":"Update on the management of central retinal artery occlusion","volume":"35","author":"Dattilo","year":"2017","journal-title":"Neurol Clin"},{"key":"2025082711422409000_13.9.e235763.4","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1001\/jamainternmed.2017.8653","article-title":"Association of vegetation size with embolic risk in patients with infective endocarditis: a systematic review and meta-analysis","volume":"178","author":"Mohananey","year":"2018","journal-title":"JAMA Intern Med"},{"key":"2025082711422409000_13.9.e235763.5","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s10792-013-9779-6","article-title":"Central retinal artery occlusion due to infective endocarditis","volume":"34","author":"Ziakas","year":"2014","journal-title":"Int Ophthalmol"},{"key":"2025082711422409000_13.9.e235763.6","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1080\/21505594.2017.1393600","article-title":"Streptococcus gallolyticus subsp. gallolyticus endocarditis isolate interferes with coagulation and activates the contact system","volume":"9","author":"Isenring","year":"2018","journal-title":"Virulence"},{"key":"2025082711422409000_13.9.e235763.7","doi-asserted-by":"crossref","first-page":"e161","DOI":"10.1016\/j.jfo.2014.03.013","article-title":"Ophthalmic artery occlusion as a complication of infectious endocarditis","volume":"37","author":"Wathek","year":"2014","journal-title":"J Fr Ophtalmol"},{"key":"2025082711422409000_13.9.e235763.8","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1001\/jama.2018.7596","article-title":"Management considerations in infective endocarditis: a review","volume":"320","author":"Wang","year":"2018","journal-title":"JAMA"},{"key":"2025082711422409000_13.9.e235763.9","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/S0140-6736(15)00067-7","article-title":"Infective endocarditis","volume":"387","author":"Cahill","year":"2016","journal-title":"The Lancet"},{"key":"2025082711422409000_13.9.e235763.10","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.ajo.2018.08.027","article-title":"Stroke risk and risk factors in patients with central retinal artery occlusion","volume":"196","author":"Lavin","year":"2018","journal-title":"Am J Ophthalmol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-235763","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:42:31Z","timestamp":1756320151000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-235763"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":10,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2020,9,2]]},"published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1136\/bcr-2020-235763"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-235763","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2020,9]]}}}