{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T13:27:25Z","timestamp":1769520445116,"version":"3.49.0"},"reference-count":16,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,1,25]]},"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:p>Hypnic headache (HH) is a rare, primary headache syndrome that invariably occurs during sleep and wakes the patient. Acoustic neuroma (AN) is a benign tumour that uncommonly presents with isolated headache. Here, we describe a patient with AN that presented with an HH-like syndrome. A 40-year-old woman presented with 4\u2009months of generalised, throbbing, nocturnal headaches that woke her from sleep. Neurological examination was unremarkable. Retrospectively, she reported a 4-year history of mild, bilateral tinnitus. Neuroimaging demonstrated a large, left-sided AN in the cerebellopontine angle without obstructive hydrocephalus. Gamma knife radiosurgery controlled tumour growth. One year after radiosurgery, she became nocturnal headache-free. AN has not previously been described as presenting with an HH-like syndrome. There are four previous reports of an HH-like syndrome secondary to intracranial masses. In all cases, patients became headache-free following surgery. This advocates for neuroimaging to exclude structural causes.<\/jats:p>","DOI":"10.1136\/bcr-2020-235830","type":"journal-article","created":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T10:50:34Z","timestamp":1615287034000},"page":"e235830","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Acoustic neuroma presenting as a hypnic headache"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7944-9924","authenticated-orcid":false,"given":"Bryan","family":"Ceronie","sequence":"first","affiliation":[{"name":"Cardiology, West Middlesex University Hospital, Isleworth, London, UK"},{"name":"Neurology, St George's University Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2994-1272","authenticated-orcid":false,"given":"Frederick","family":"Green","sequence":"additional","affiliation":[{"name":"Ear, Nose and Throat Surgery, Barts Health NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver Charles","family":"Cockerell","sequence":"additional","affiliation":[{"name":"Neurology, The London Clinic, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,3,9]]},"reference":[{"key":"2025082804293000000_14.3.e235830.1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413495967"},{"key":"2025082804293000000_14.3.e235830.2","doi-asserted-by":"publisher","DOI":"10.1177\/0333102414537914"},{"key":"2025082804293000000_14.3.e235830.3","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/head.12460","article-title":"From wakefulness to sleep: migraine and hypnic headache association in a series of 23 patients","volume":"55","author":"Ruiz","year":"2015","journal-title":"Headache"},{"key":"2025082804293000000_14.3.e235830.4","first-page":"1","volume-title":"The International classification of headache disorders","volume":"38","year":"2018"},{"key":"2025082804293000000_14.3.e235830.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2008.01284.x"},{"key":"2025082804293000000_14.3.e235830.6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2008.01701.x"},{"key":"2025082804293000000_14.3.e235830.7","doi-asserted-by":"publisher","DOI":"10.1177\/0333102409352911"},{"key":"2025082804293000000_14.3.e235830.8","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2003.03195.x"},{"key":"2025082804293000000_14.3.e235830.9","doi-asserted-by":"publisher","DOI":"10.1177\/0333102414535996"},{"key":"2025082804293000000_14.3.e235830.10","unstructured":"Corbridge R , Warner G , Patel S . 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