{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:26:23Z","timestamp":1760217983178,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,11,25]]},"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Pubic osteomyelitis is a rare and often late-onset complication of radiation therapy and surgery for vulvar and vaginal carcinoma. It typically presents with vulvar pain, fever, vaginal discharge and\/or gait disorders. Pubic osteomyelitis is often accompanied by fistulas or wound dehiscence in the pelvic area. Its accurate diagnosis and treatment are challenging and require a multidisciplinary team effort. In our patients, multiple combined surgical procedures, long-term antibiotic treatment and days to weeks of hospital admission were necessary to treat pubic osteomyelitis. We emphasise the importance of timely and adequate diagnosis and multidisciplinary approach resulting in a course of treatment that is as effective as possible, limiting the impact on quality of life, which is generally high in this group of patients.<\/jats:p>","DOI":"10.1136\/bcr-2020-236289","type":"journal-article","created":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T18:23:15Z","timestamp":1610475795000},"page":"e236289","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Multidisciplinary management of patients with pubic osteomyelitis, a rare but serious complication after surgery and radiation therapy for advanced gynaecological cancer"],"prefix":"10.1136","volume":"14","author":[{"given":"Ilse","family":"Haveman","sequence":"first","affiliation":[{"name":"Obstetrics and Gynaecology, Radboudumc, Nijmegen, Gelderland, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne M","family":"van Altena","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, Radboudumc, Nijmegen, Gelderland, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte PA","family":"Verschuren","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, Radboudumc, Nijmegen, Gelderland, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0674-9405","authenticated-orcid":false,"given":"Johanna WM","family":"Aarts","sequence":"additional","affiliation":[{"name":"Amsterdam UMC, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,1,11]]},"reference":[{"key":"2025082722301987000_14.1.e236289.1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3857\/roj.2012.30.1.20","article-title":"Treatment outcome in patients with vulvar cancer: comparison of concurrent radiotherapy to postoperative radiotherapy","volume":"30","author":"Lee","year":"2012","journal-title":"Radiat Oncol J"},{"key":"2025082722301987000_14.1.e236289.2","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000000117"},{"key":"2025082722301987000_14.1.e236289.3","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/0002-9378(90)90036-7","article-title":"Interstitial radiotherapy for the treatment of advanced or recurrent vulvar and distal vaginal malignancy","volume":"162","author":"Hoffman","year":"1990","journal-title":"Am J Obstet Gynecol"},{"key":"2025082722301987000_14.1.e236289.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(98)80059-7"},{"key":"2025082722301987000_14.1.e236289.5","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.medmal.2019.10.012","article-title":"Pubic osteomyelitis: epidemiology and factors associated with treatment failure","volume":"50","author":"Becker","year":"2020","journal-title":"Med Mal Infect"},{"key":"2025082722301987000_14.1.e236289.6","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.ygyno.2005.12.007","article-title":"Pelvic radiation necrosis and osteomyelitis following chemoradiation for advanced stage vulvar and cervical carcinoma","volume":"101","author":"Micha","year":"2006","journal-title":"Gynecol Oncol"},{"key":"2025082722301987000_14.1.e236289.7","first-page":"40","article-title":"Skull base or cervical vertebral osteomyelitis following chemoradiotherapy for pharyngeal carcinoma: a serious but treatable complication","volume":"8","author":"Lalani","year":"2018","journal-title":"Clin Transl Radiat Oncol"},{"key":"2025082722301987000_14.1.e236289.8","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.urology.2014.11.020","article-title":"Pubic symphysis osteomyelitis in the prostate cancer survivor: clinical presentation, evaluation, and management","volume":"85","author":"Gupta","year":"2015","journal-title":"Urology"},{"key":"2025082722301987000_14.1.e236289.9","doi-asserted-by":"publisher","DOI":"10.1097\/01.md.0000091180.93122.1c"},{"key":"2025082722301987000_14.1.e236289.10","doi-asserted-by":"crossref","first-page":"83","DOI":"10.4103\/0300-1652.128179","article-title":"Osteomyelits of the pubic bone with vesicocutaneous - vesicovaginal fistula: A delayed complication of post-cervical cancer radiotherapy","volume":"55","author":"Salunke","year":"2014","journal-title":"Niger Med J"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-236289","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:30:27Z","timestamp":1756359027000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-236289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,1,11]]},"published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1136\/bcr-2020-236289"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-236289","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}