{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T22:26:16Z","timestamp":1784672776616,"version":"3.55.0"},"reference-count":10,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T00:00:00Z","timestamp":1609372800000},"content-version":"unspecified","delay-in-days":30,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,11,10]]},"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:p>Cardiac tamponade as the initial presentation of hypothyroidism is extremely rare. We report the case of a 48-year-old man admitted for acute respiratory distress, with cardiac ultrasound showing compressive pericardial effusion. Percutaneous pericardiocentesis was performed leading to a rapid clinical improvement. Laboratory tests confirmed severe hypothyroidism related to Hashimoto\u2019s disease. Despite hormone replacement therapy, pericardial effusion recurred after 3\u2009weeks, requiring surgical drainage. Pericardial histology highlighted slight chronic fibrous pericarditis. The cardiac ultrasound scan performed 4\u2009months later showed a well-tolerated chronic pericardial effusion. In conclusion, hypothyroidism should be suspected in case of cardiac tamponade especially in the absence of tachycardia, or in winter when myxoedema is prone to decompensation. Prognosis is generally good under hormone replacement therapy but ultrasound monitoring should be carried out at least until euthyroidism is achieved.<\/jats:p>","DOI":"10.1136\/bcr-2020-236342","type":"journal-article","created":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T17:45:19Z","timestamp":1609436719000},"page":"e236342","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Myxoedematous tamponade as initial presentation of Hashimoto\u2019s thyroiditis"],"prefix":"10.1136","volume":"13","author":[{"given":"Benjamin","family":"Casez","sequence":"first","affiliation":[{"name":"Cardiovascular Institute, Mutual Hospital Group of Grenoble, Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2819-325X","authenticated-orcid":false,"given":"Alain","family":"Roug\u00e9","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, Mutual Hospital Group of Grenoble, Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Fourme","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, Mutual Hospital Group of Grenoble, Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Mons\u00e9gu","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, Mutual Hospital Group of Grenoble, Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,12,31]]},"reference":[{"key":"2025082722524883000_13.12.e236342.1","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/S0140-6736(75)91571-8","article-title":"Effusions into body cavities in hypothyroidism","volume":"1","author":"Sachdev","year":"1975","journal-title":"Lancet"},{"key":"2025082722524883000_13.12.e236342.2","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2015.00062","article-title":"Physiology of pericardial fluid production and drainage","volume":"6","author":"Vogiatzidis","year":"2015","journal-title":"Front Physiol"},{"key":"2025082722524883000_13.12.e236342.3","doi-asserted-by":"crossref","unstructured":"Bajaj R , Mehrzad R , Singh K , et al . Cardiac tamponade in hypothyroidism. 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