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Nasal endoscopy showed irregular mucosa of the nasal cavity with easily bleeding. Nasal biopsy reported as extranodal Natural Killer\/T cell lymphoma, nasal type. In-situ hybridisation for Epstein-Barr encoding region was positive. He was treated with six cycles of gemcitabine, oxaliplatin and L-asparaginase and peripheral blood stem cell transplant. After the treatment, he was asymptomatic until 9 months where he had splenic abscess and undergone splenectomy. He was asymptomatic of the disease for 2 years.<\/jats:p>","DOI":"10.1136\/bcr-2020-236436","type":"journal-article","created":{"date-parts":[[2021,6,22]],"date-time":"2021-06-22T12:00:39Z","timestamp":1624363239000},"page":"e236436","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Extranodal NK\/T cell lymphoma, nasal type: a rare diagnosis with common nasal presentation"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9566-3007","authenticated-orcid":false,"given":"Siti Sarah","family":"Mohd Ramli","sequence":"first","affiliation":[{"name":"Otorhinolaryngology, Pusat Perubatan Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7683-2143","authenticated-orcid":false,"given":"Salina","family":"Husain","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology, Pusat Perubatan Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4897-9927","authenticated-orcid":false,"given":"Yin Ping","family":"Wong","sequence":"additional","affiliation":[{"name":"Pathology, Pusat Perubatan Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,6,22]]},"reference":[{"key":"2025082711150851000_14.6.e236436.1","first-page":"1043","article-title":"Treatment and outcomes of Centrofacial NK\/T cell lymphoma nasal type: a report of 8 cases and literature review","volume":"3","author":"Sellami","year":"2015","journal-title":"Annals of Clinical Pathology"},{"key":"2025082711150851000_14.6.e236436.2","doi-asserted-by":"publisher","DOI":"10.1002\/hon.847"},{"key":"2025082711150851000_14.6.e236436.3","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s13045-017-0452-9","article-title":"The diagnosis and management of NK\/T-cell lymphomas","volume":"10","author":"Tse","year":"2017","journal-title":"J Hematol Oncol"},{"key":"2025082711150851000_14.6.e236436.4","first-page":"3055","article-title":"Pathological and clinical characteristics of 1,248 non-Hodgkin's lymphomas from a regional cancer hospital in Shandong, China","volume":"12","author":"Liu","year":"2011","journal-title":"Asian Pac J Cancer Prev"},{"key":"2025082711150851000_14.6.e236436.5","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdf033"},{"key":"2025082711150851000_14.6.e236436.6","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.16.4558"},{"key":"2025082711150851000_14.6.e236436.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.beha.2013.04.003"},{"key":"2025082711150851000_14.6.e236436.8","doi-asserted-by":"publisher","DOI":"10.3960\/jslrt.51.21"},{"key":"2025082711150851000_14.6.e236436.9","first-page":"58","article-title":"Extranodal NK\/T-cell lymphoma, nasal type, primarily involving ovary","volume":"9","author":"Stensland","year":"2017","journal-title":"Human Pathology: Case Reports"},{"key":"2025082711150851000_14.6.e236436.10","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20015"},{"key":"2025082711150851000_14.6.e236436.11","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.2001.01104.x"},{"key":"2025082711150851000_14.6.e236436.12","doi-asserted-by":"crossref","first-page":"997","DOI":"10.2147\/OTT.S153942","article-title":"Prognostic significance of Epstein-Barr virus DNA in NK\/T-cell lymphoma: a meta-analysis","volume":"11","author":"Fei","year":"2018","journal-title":"Onco Targets Ther"},{"key":"2025082711150851000_14.6.e236436.13","unstructured":"Chan J JE , Ralfakiaer E , Yh K . 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