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Cerebrospinal fluid analysis by PCR revealed the presence of VZV, making the diagnosis of acute varicella meningitis. The patient had immunoglobulin studies consistent with a history of primary VZV infection, thus confirming reactivation of VZV rather than primary infection. The patient was treated with acyclovir for 14 days and recovered fully. Her neonate was delivered full term without any evidence of vertical transmission. This is only the second reported case of VZV meningitis in a pregnant patient in the medical literature, and the first case in the US that was reported.<\/jats:p>","DOI":"10.1136\/bcr-2020-236644","type":"journal-article","created":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T10:58:32Z","timestamp":1614077912000},"page":"e236644","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Varicella zoster meningitis in a pregnant woman with uncontrolled type 1 diabetes mellitus"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1571-2150","authenticated-orcid":false,"given":"Laura","family":"Mroue","sequence":"first","affiliation":[{"name":"Obstetrics-Gynecology, Detroit Medical Center, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harpreet","family":"Brar","sequence":"additional","affiliation":[{"name":"Obstetrics-Gynecology, Detroit Medical Center, Hamtramck, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Gonik","sequence":"additional","affiliation":[{"name":"Obstetrics-Gynecology, Detroit Medical Center, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,2,23]]},"reference":[{"key":"2025082712500480000_14.2.e236644.1","doi-asserted-by":"crossref","first-page":"e00446","DOI":"10.1016\/j.idcr.2018.e00446","article-title":"Varicella zoster aseptic meningitis: report of an atypical case in an immunocompetent patient treated with oral valacyclovir","volume":"13","author":"Gnoni","year":"2018","journal-title":"IDCases"},{"key":"2025082712500480000_14.2.e236644.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2011.02983.x"},{"key":"2025082712500480000_14.2.e236644.3","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1086\/510206","article-title":"Recommendations for the management of herpes zoster","volume":"44 Suppl 1","author":"Dworkin","year":"2007","journal-title":"Clin Infect Dis"},{"key":"2025082712500480000_14.2.e236644.4","first-page":"1","article-title":"Varicella zoster virus meningitis in a young immunocompetent adult without rash: a misleading clinical presentation","volume":"2014","author":"Pasedag","year":"2014","journal-title":"Case Rep Neurol Med"},{"key":"2025082712500480000_14.2.e236644.5","unstructured":"CDC . 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