{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T16:55:49Z","timestamp":1781715349947,"version":"3.54.5"},"reference-count":26,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,10,1]]},"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>Osteomyelitis is a rare initial presentation of HIV. We report a case of a 25-year-old, apparently well man presenting with a traumatic, pathological fracture of the right radius. He had a 2-week history of low-grade fever, swelling and purulent discharge of the radial aspect of his right forearm. Osteomyelitis, secondary bacteraemia and pneumonia were clues that led physicians to test for HIV. Multiple debridement, sequestrectomy and vacuum-assisted closure were done. Tissue cultures revealed <jats:italic>Mycobacterium tuberculosis<\/jats:italic> (TB) and methicillin-sensitive <jats:italic>Staphylococcus aureus<\/jats:italic>. He was treated successfully with 6\u2009weeks of culture-guided intravenous oxacillin, staphylococcal decontamination and first-line anti-TB regimen (rifampicin, isoniazid, ethambutol, pyrazinamide). Antiretroviral agents were started thereafter. Successful infection control and preservation of limb functionality was achieved with a multidisciplinary team approach. To our knowledge this is the first reported case of an adult patient with HIV presenting with tuberculous and pyogenic osteomyelitis of the radial bone.<\/jats:p>","DOI":"10.1136\/bcr-2020-236802","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T17:05:47Z","timestamp":1603818347000},"page":"e236802","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["AIDS presenting as radial bone tuberculosis and pyogenic methicillin-sensitive <i>Staphylococcus aureus<\/i> osteomyelitis"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0040-2280","authenticated-orcid":false,"given":"Nigel Jeronimo Cortez","family":"Santos","sequence":"first","affiliation":[{"name":"Department of Medicine, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle Dominique Villegas","family":"Tomacruz","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances Lina","family":"Lantion-Ang","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes and Metabolism Department of Medicine, Philippine General Hospital University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula Veronica San Juan","family":"Reyes","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Philippine General Hospital, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,10,27]]},"reference":[{"key":"2025082801160338000_13.10.e236802.1","unstructured":"World Health Organization . 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