{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T21:53:12Z","timestamp":1789509192556,"version":"build-2803163510"},"reference-count":11,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,11,10]]},"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:p>A 49-year-old man with a recent history of atrial tachycardia and intracardiac thrombus presented to the emergency department with melena and cardiac tamponade. Physical examination was notable for a vascular mass at the right lower gingival sulcus and a right chest wall nodule. Enteroscopy revealed a target lesion with friable ulcer in the gastric body. Cardiac MRI revealed a large right atrial mass, previously thought to represent thrombus. The patient was ultimately diagnosed with primary cardiac angiosarcoma (PCAS) by histopathology of gingival, gastric and subcutaneous lesions. This case illustrates the significant morbidity and mortality resulting from aggressive local invasion and growth of PCAS, as well as the challenge of differentiating between primary thrombosis and vascular malignancy. Misdiagnosis of this elusive clinical entity may be costly, potentially resulting in delay of intervention and adverse effects of alternate therapies such as anticoagulation.<\/jats:p>","DOI":"10.1136\/bcr-2020-236806","type":"journal-article","created":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T14:46:03Z","timestamp":1607525163000},"page":"e236806","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Primary cardiac angiosarcoma masquerading as intracardiac thrombus"],"prefix":"10.1136","volume":"13","author":[{"given":"Nicholas","family":"Villano","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William P","family":"Flavin","sequence":"additional","affiliation":[{"name":"Department of Neurology, UCLA Medical Center, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela","family":"Tsing","sequence":"additional","affiliation":[{"name":"Division of Hospital Medicine, West Los Angeles VA Medical Center, Los Angeles, California, USA"},{"name":"David Geffen School of Medicine at UCLA, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,12,9]]},"reference":[{"key":"2025082802055526000_13.12.e236806.1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.4103\/0972-3919.202233","article-title":"Unusual presentation of rare cardiac tumor: the role of F-18-Fluorodeoxyglucose positron emission tomography\/computed tomography","volume":"32","author":"Taywade","year":"2017","journal-title":"Indian J Nucl Med"},{"key":"2025082802055526000_13.12.e236806.2","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.889875"},{"key":"2025082802055526000_13.12.e236806.3","doi-asserted-by":"crossref","DOI":"10.1093\/ehjcr\/ytz027","article-title":"Cardiac tamponade as first manifestation of atrial angiosarcoma","volume":"3","author":"Concha","year":"2019","journal-title":"Eur Heart J Case Rep"},{"key":"2025082802055526000_13.12.e236806.4","doi-asserted-by":"crossref","first-page":"e483","DOI":"10.1016\/j.athoracsur.2016.11.032","article-title":"Entire Circumferential Reconstruction of the Right Atrium Surrounded by Angiosarcoma","volume":"103","author":"Hibino","year":"2017","journal-title":"Ann Thorac Surg"},{"key":"2025082802055526000_13.12.e236806.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2013.09.012"},{"key":"2025082802055526000_13.12.e236806.6","article-title":"Case report of a sub-occluding thrombus in thoracic aorta: what is the origin?","volume":"3","author":"Campana","year":"2019","journal-title":"Eur Heart J Case Rep"},{"key":"2025082802055526000_13.12.e236806.7","doi-asserted-by":"publisher","DOI":"10.1007\/s10016-004-0067-9"},{"key":"2025082802055526000_13.12.e236806.8","doi-asserted-by":"crossref","DOI":"10.1186\/s12885-019-6450-2","article-title":"Fast growing angiosarcoma of the right atrium after radiofrequency catheter ablation: a missed diagnosis or misdiagnosis case report","volume":"20","author":"Yu","year":"2020","journal-title":"BMC Cancer"},{"key":"2025082802055526000_13.12.e236806.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2008.11.026"},{"key":"2025082802055526000_13.12.e236806.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.03.065"},{"key":"2025082802055526000_13.12.e236806.11","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.783126"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-236806","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:06:06Z","timestamp":1756371966000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-236806"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":11,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2020,12,9]]},"published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1136\/bcr-2020-236806"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-236806","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12]]}}}