{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:38:28Z","timestamp":1782603508423,"version":"3.54.5"},"reference-count":25,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/bmj.com\/coronavirus\/usage"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,10,9]]},"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:p>The novel COVID-19 has had an unprecedented and devastating spread internationally. COVID-19 infection can lead to a number of cardiovascular sequelae, including heart failure, which may portend worse clinical outcomes. Here, we report a rare case of a 57-year-old woman who developed acute left ventricular systolic dysfunction with apical ballooning consistent with takotsubo cardiomyopathy (TCM), and mixed cardiogenic and septic shock in the setting of COVID-19 disease. We briefly review the pathophysiology and diagnosis of TCM (also described as apical ballooning syndrome and stress-induced cardiomyopathy). Additionally, this case highlights the importance of a multidisciplinary approach to clinical decision-making and resource allocation in diagnosis and management of critical illness in the setting of the ongoing international COVID-19 pandemic.<\/jats:p>","DOI":"10.1136\/bcr-2020-236811","type":"journal-article","created":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T09:45:33Z","timestamp":1607766333000},"page":"e236811","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":21,"title":["COVID-19-associated takotsubo cardiomyopathy"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4112-597X","authenticated-orcid":false,"given":"Joanne Michelle Dumlao","family":"Gomez","sequence":"first","affiliation":[{"name":"Cardiology, Rush University Medical Center, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gatha","family":"Nair","sequence":"additional","affiliation":[{"name":"Cardiology, Rush University Medical Center, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prema","family":"Nanavaty","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Medicine, Rush University Medical Center, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anupama","family":"Rao","sequence":"additional","affiliation":[{"name":"Cardiology, Rush University Medical Center, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Marinescu","sequence":"additional","affiliation":[{"name":"Cardiology, Rush University Medical Center, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tisha","family":"Suboc","sequence":"additional","affiliation":[{"name":"Cardiology, Rush University Medical Center, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,12,12]]},"reference":[{"key":"2025082700251636000_13.12.e236811.1","unstructured":"Summary @ www.cdc.gov. 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