{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:07:16Z","timestamp":1756339636525,"version":"3.44.0"},"reference-count":17,"publisher":"BMJ","issue":"10","license":[{"start":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:00:00Z","timestamp":1604016000000},"content-version":"unspecified","delay-in-days":29,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,9,30]]},"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>A 66-year-old male patient who had received chemoradiotherapy (CRT) for laryngeal cancer 2\u2009years ago visited a local doctor complaining of dyspnoea and wheezing. CT scan showed narrowing of the trachea caused by a tumour. We intubated the trachea over the tumour using a bronchoscope. A week later, the truncated tracheal tumour obstructed the tracheal tube, compromising the patient\u2019s breathing. We removed the obstructed tube and inserted a new one. We submitted the tissue from the tube to a pathologist. Histopathological diagnosis was pleomorphic carcinoma, a subtype of sarcomatoid carcinoma. The mechanism of epithelial\u2013mesenchymal transition (EMT) occurring after CRT was detected in the tumour. Because he had undergone CRT for laryngeal cancer, surgery was not indicated, and we started radiation therapy. Sarcomatoid carcinomas including pleomorphic carcinoma of the trachea are extremely rare, with few reported cases, and EMT is associated with this histological type and CRT.<\/jats:p>","DOI":"10.1136\/bcr-2020-236819","type":"journal-article","created":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T17:11:12Z","timestamp":1604077872000},"page":"e236819","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Pleomorphic carcinoma of the trachea after chemoradiotherapy for laryngeal cancer"],"prefix":"10.1136","volume":"13","author":[{"given":"Hirotaka","family":"Saikawa","sequence":"first","affiliation":[{"name":"Division of Pulmonary Medicine, Allergy, and Rheumatology, Department of Internal Medicine, Iwate Medical University, Iwate, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyuki","family":"Uesugi","sequence":"additional","affiliation":[{"name":"Department of Molecular Diagnostic 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