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In this article, we highlight the steps taken to diagnose this rare pathology, explain its pathophysiology and management.<\/jats:p>","DOI":"10.1136\/bcr-2020-236855","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T18:18:21Z","timestamp":1608661101000},"page":"e236855","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["SMAD4 juvenile polyposis syndrome and hereditary haemorrhagic telangiectasia presenting in a middle-aged man as a large fungating gastric mass, polyposis in both upper and lower GI tract and iron deficiency anaemia, with no known family history"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4978-374X","authenticated-orcid":false,"given":"Wendy","family":"Chang","sequence":"first","affiliation":[{"name":"General Surgery, Mackay Base Hospital, Mackay, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Renaut","sequence":"additional","affiliation":[{"name":"Pathology, Queensland Pathology, Herston, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Casper","family":"Pretorius","sequence":"additional","affiliation":[{"name":"General Surgery, Mackay Base Hospital, Mackay, Queensland, Australia"},{"name":"James Cook University School of Medicine, Douglas, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,12,22]]},"reference":[{"key":"2025082703383481000_13.12.e236855.1","doi-asserted-by":"crossref","unstructured":"Muto M , Yao K , Sano Y . 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