{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T12:21:02Z","timestamp":1792844462294,"version":"4.5.0"},"reference-count":35,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,6,11]]},"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:p>A 44-year-old man with a history of renal transplantation presented with right lower abdominal wall swelling, redness and pain. A bacterial abscess was drained, and he was discharged home with oral antibiotics. After failing to improve, he returned to the hospital, where he was briefly treated with intravenous antibiotics and discharged home again. The patient returned 5\u2009days later, reporting worsening right groin swelling that extended into the ipsilateral scrotum. Imaging revealed a persistent fluid collection in the region, and he was taken for surgical debridement. Tissue immunochemistry and histopathological evaluation identified cytomegalovirus infection. Plasma quantitative PCR for cytomegalovirus demonstrated high viraemia. The patient was successfully treated with intravenous ganciclovir, followed by oral valganciclovir, with resolution of the skin changes. Persistent hydrocele with epididymitis on imaging suggests that this process may have been the source of the cutaneous cytomegalovirus infection.<\/jats:p>","DOI":"10.1136\/bcr-2020-236903","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T11:50:16Z","timestamp":1625485816000},"page":"e236903","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Cytomegalovirus skin disease in a kidney transplant patient"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2854-243X","authenticated-orcid":false,"given":"Miguel Enrique","family":"Cervera-Hernandez","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, Montefiore Medical Center, Bronx, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Ikemura","sequence":"additional","affiliation":[{"name":"Department of Pathology, Montefiore Medical Center, Bronx, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret E","family":"McCort","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, Montefiore Medical Center, Bronx, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,7,5]]},"reference":[{"key":"2025082802252445000_14.7.e236903.1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(04)01202-2"},{"key":"2025082802252445000_14.7.e236903.2","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13512"},{"key":"2025082802252445000_14.7.e236903.3","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14208"},{"key":"2025082802252445000_14.7.e236903.4","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/92.1.96"},{"key":"2025082802252445000_14.7.e236903.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2010.01.005"},{"key":"2025082802252445000_14.7.e236903.6","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002191"},{"key":"2025082802252445000_14.7.e236903.7","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jdcr.2019.04.017","article-title":"Cytomegalovirus-induced vasculopathy and anogenital skin ulcers in a patient with multiple myeloma","volume":"6","author":"Tanaka","year":"2020","journal-title":"JAAD Case Rep"},{"key":"2025082802252445000_14.7.e236903.8","unstructured":"The Food and Drug Administration . Ganciclovir injection label [Internet]. Available: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2017\/209347lbl.pdf [Accessed 2 Mar 2020]."},{"key":"2025082802252445000_14.7.e236903.9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07456.x"},{"key":"2025082802252445000_14.7.e236903.10","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3062.2001.003001047.x"},{"key":"2025082802252445000_14.7.e236903.11","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/tid.12536","article-title":"A potential role for cytomegalovirus in a facial ulcer in a renal transplant recipient","volume":"18","author":"Ezzatzadegan Jahromi","year":"2016","journal-title":"Transpl Infect Dis"},{"key":"2025082802252445000_14.7.e236903.12","first-page":"1","article-title":"Unusual manifestations of acute cytomegalovirus infection in solid organ transplant hosts: a report of two cases","volume":"2017","author":"Mena Lora","year":"2017","journal-title":"Case Rep Transplant"},{"key":"2025082802252445000_14.7.e236903.13","doi-asserted-by":"crossref","first-page":"e145","DOI":"10.1111\/ajd.12921","article-title":"Cytomegalovirus ulcers following radiotherapy for a Marjolin ulcer in a renal transplant recipient","volume":"60","author":"Wang","year":"2019","journal-title":"Australas J Dermatol"},{"key":"2025082802252445000_14.7.e236903.14","first-page":"572","article-title":"[Cytomegalovirus cellulitis]","volume":"62","author":"Ruiz Lascano","year":"2002","journal-title":"Medicina"},{"key":"2025082802252445000_14.7.e236903.15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2007.00273.x"},{"key":"2025082802252445000_14.7.e236903.16","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1001\/jamadermatol.2014.5110","article-title":"Skin leg ulcer in an immunocompromised patient with Pseudomonas aeruginosa sepsis. Cytomegalovirus ulcer","volume":"151","author":"Lloret-Ruiz","year":"2015","journal-title":"JAMA Dermatol"},{"key":"2025082802252445000_14.7.e236903.17","doi-asserted-by":"publisher","DOI":"10.1093\/ndtplus\/sfq176"},{"key":"2025082802252445000_14.7.e236903.18","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1590\/abd1806-4841.20163989","article-title":"Cutaneous involvement by cytomegalovirus in a renal transplant recipient as an indicator of severe systemic infection","volume":"91","author":"Neumann","year":"2016","journal-title":"An Bras Dermatol"},{"key":"2025082802252445000_14.7.e236903.19","doi-asserted-by":"publisher","DOI":"10.1177\/1203475416650643"},{"key":"2025082802252445000_14.7.e236903.20","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.126.11.1498"},{"key":"2025082802252445000_14.7.e236903.21","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/DAD.0b013e3182539eee","article-title":"Atypical presentation of exophytic herpes simplex virus type 2 with concurrent cytomegalovirus infection: a significant pitfall in diagnosis","volume":"35","author":"Garib","year":"2013","journal-title":"Am J Dermatopathol"},{"key":"2025082802252445000_14.7.e236903.22","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1977.01640110089015"},{"key":"2025082802252445000_14.7.e236903.23","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0190-9622(83)70212-4","article-title":"Histologically specific skin lesions in disseminated cytomegalovirus infection","volume":"9","author":"Pariser","year":"1983","journal-title":"J Am Acad Dermatol"},{"key":"2025082802252445000_14.7.e236903.24","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-198812000-00009"},{"key":"2025082802252445000_14.7.e236903.25","doi-asserted-by":"publisher","DOI":"10.1093\/ndtplus\/sfq082"},{"key":"2025082802252445000_14.7.e236903.26","first-page":"329","article-title":"Diagnosis of disseminated cytomegalovirus infection and pneumonitis in a heart transplant recipient by skin biopsy: case report","volume":"10","author":"Rees","year":"1991","journal-title":"J Heart Lung Transplant"},{"key":"2025082802252445000_14.7.e236903.27","doi-asserted-by":"publisher","DOI":"10.1016\/S0210-4806(08)73903-2"},{"key":"2025082802252445000_14.7.e236903.28","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.jaad.2009.11.007","article-title":"Cytomegalovirus-induced cutaneous vasculopathy and perianal ulceration","volume":"64","author":"Ryan","year":"2011","journal-title":"J Am Acad Dermatol"},{"key":"2025082802252445000_14.7.e236903.29","doi-asserted-by":"crossref","DOI":"10.5070\/D3251042608","article-title":"Cutaneous cytomegalovirus manifestations, diagnosis, and treatment: a review","volume":"25","author":"Drozd","year":"2019","journal-title":"Dermatol Online J"},{"key":"2025082802252445000_14.7.e236903.30","doi-asserted-by":"publisher","DOI":"10.1086\/315184"},{"key":"2025082802252445000_14.7.e236903.31","doi-asserted-by":"publisher","DOI":"10.3109\/01902149809046050"},{"key":"2025082802252445000_14.7.e236903.32","doi-asserted-by":"publisher","DOI":"10.1006\/viro.2000.0367"},{"key":"2025082802252445000_14.7.e236903.33","doi-asserted-by":"crossref","DOI":"10.1111\/tid.12998","article-title":"Native kidney cytomegalovirus nephritis and cytomegalovirus prostatitis in a kidney transplant recipient","volume":"21","author":"Tan","year":"2019","journal-title":"Transpl Infect Dis"},{"key":"2025082802252445000_14.7.e236903.34","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0022-5347(17)37811-4","article-title":"Cytomegalovirus epididymitis following renal transplantation","volume":"146","author":"McCarthy","year":"1991","journal-title":"J Urol"},{"key":"2025082802252445000_14.7.e236903.35","first-page":"151","article-title":"Post-transplantation epididymitis associated with cytomegalovirus","volume":"39","author":"Kini","year":"1996","journal-title":"Indian J Pathol Microbiol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-236903","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:25:35Z","timestamp":1756373135000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-236903"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":35,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2021,7,5]]},"published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1136\/bcr-2020-236903"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-236903","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}