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This case highlights the importance of regular clinical assessment and re-evaluation is key in identifying emerging features such as eosinophilia, rash and organ dysfunction, which can secure the diagnosis. Furthermore, the case also highlights that acetazolamide may be a rare cause of DRESS syndrome.<\/jats:p>","DOI":"10.1136\/bcr-2020-236966","type":"journal-article","created":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T12:10:14Z","timestamp":1610971814000},"page":"e236966","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Drug reaction with eosinophilia and systemic symptoms syndrome secondary to acetazolamide associated with markedly elevated procalcitonin"],"prefix":"10.1136","volume":"14","author":[{"given":"Syed Basharat","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Immunology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sacha","family":"Schweikert","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Sir Charles Gairdner Hospital, Nedlands, Western 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