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Examination identified weakness in all four limbs and areflexia, suggesting a peripheral neuromuscular disorder. Investigations were consistent with Guillain-Barr\u00e9 syndrome and additional COVID-19 (SARS-CoV-2) infection. The patient improved after immunoglobulin treatment. At least four cases of Guillain-Barr\u00e9 syndrome have been reported in the literature with concurrent COVID-19 illness in whom respiratory signs appeared a few days after the onset of neurological signs. With the incubation period for COVID-19 respiratory symptoms believed to be up to 14 days, it is possible that neurological symptoms could develop before respiratory and other symptoms. During the current pandemic, presence of concurrent COVID-19 infection needs to be considered in patients presenting with Guillain-Barr\u00e9 syndrome.<\/jats:p>","DOI":"10.1136\/bcr-2020-236978","type":"journal-article","created":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T17:16:41Z","timestamp":1600103801000},"page":"e236978","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Guillain-Barr\u00e9 syndrome presenting with COVID-19 infection"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0147-2216","authenticated-orcid":false,"given":"Nasir","family":"Ameer","sequence":"first","affiliation":[{"name":"Medicine, Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea, Essex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7884-0403","authenticated-orcid":false,"given":"Kalyan Mansukhbhai","family":"Shekhda","sequence":"additional","affiliation":[{"name":"Medicine, Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea, Essex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann","family":"Cheesman","sequence":"additional","affiliation":[{"name":"Neurology, Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea, Essex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,9,14]]},"reference":[{"key":"2025082711373934000_13.9.e236978.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00339-1"},{"key":"2025082711373934000_13.9.e236978.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1114525"},{"key":"2025082711373934000_13.9.e236978.3","doi-asserted-by":"publisher","DOI":"10.1136\/practneurol-2014-000937"},{"key":"2025082711373934000_13.9.e236978.4","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1097\/CM9.0000000000000722","article-title":"Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study","volume":"133","author":"Ren","year":"2020","journal-title":"Chin Med J"},{"key":"2025082711373934000_13.9.e236978.5","first-page":"1","article-title":"2019 novel coronavirus (COVID-19) outbreak: a review of the current literature","volume":"4","author":"Sahin","year":"2020","journal-title":"EJMO"},{"key":"2025082711373934000_13.9.e236978.6","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2017.13.3.227"},{"key":"2025082711373934000_13.9.e236978.7","article-title":"Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China","author":"Mao","year":"2020","journal-title":"JAMA Neurol"},{"key":"2025082711373934000_13.9.e236978.8","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2020.00518","article-title":"Neurological manifestations of COVID-19 (SARS-CoV-2): a review","volume":"11","author":"Ahmed","year":"2020","journal-title":"Front Neurol"},{"key":"2025082711373934000_13.9.e236978.9","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(20)30109-5"},{"key":"2025082711373934000_13.9.e236978.10","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jocn.2020.04.062","article-title":"Guillain Barre syndrome associated with COVID-19 infection: a case report","volume":"76","author":"Sedaghat","year":"2020","journal-title":"J Clin Neurosci"},{"key":"2025082711373934000_13.9.e236978.11","doi-asserted-by":"crossref","first-page":"2574","DOI":"10.1056\/NEJMc2009191","article-title":"Guillain-Barr\u00e9 syndrome associated with SARS-CoV-2","volume":"382","author":"Toscano","year":"2020","journal-title":"N Engl J Med"},{"key":"2025082711373934000_13.9.e236978.12","unstructured":"Michael B , Easton A . 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