{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:33:32Z","timestamp":1791930812998,"version":"4.3.4"},"reference-count":11,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,5,8]]},"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p>Low-grade fibromyxoid sarcoma (LGFMS) is an uncommon soft-tissue malignancy. LGFMS preferentially affects trunks and extremities of young adults; however, occasional cases have been reported in different sites of head and neck region including oral cavity, larynx and oropharynx. LGFMS usually exhibit areas of collagenised and myxoid stroma with appearance of spindle cells in whorling pattern. It is a challenge to diagnose it accurately as most of the time it is misdiagnosed as benign neoplastic entity of spindle cells. There have been only few isolated cases of LGFMS reported in head and neck region and LGFMS originating from the parapharyngeal space has never been reported before. We recently experienced a case of low grade fibomyxoid sarcoma in parapharyngeal space of neck. LGFMS have the propensity to locally recur and to metastasise. Due to its rarity in head and neck region, there are no well-established treatment and follow-up guidelines.<\/jats:p>","DOI":"10.1136\/bcr-2020-237083","type":"journal-article","created":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T11:55:56Z","timestamp":1621857356000},"page":"e237083","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Low-grade fibromyxoid sarcoma of the parapharyngeal space: an unusual location"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8339-4399","authenticated-orcid":false,"given":"Muhammad Hammad","family":"Deewani","sequence":"first","affiliation":[{"name":"Surgery, Aga Khan University Hospital, Karachi, Sindh, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6532-2789","authenticated-orcid":false,"given":"Muhammad Hassan","family":"Danish","sequence":"additional","affiliation":[{"name":"Surgery, Aga Khan University Hospital, Karachi, Sindh, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Sohail","family":"Awan","sequence":"additional","affiliation":[{"name":"Surgery, Aga Khan University Hospital, Karachi, Sindh, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasir","family":"Ud Din","sequence":"additional","affiliation":[{"name":"Pathology & Microbiology, Aga Khan University Hospital, Karachi, Sindh, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,5,24]]},"reference":[{"key":"2025082708260944000_14.5.e237083.1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/88.5.615"},{"key":"2025082708260944000_14.5.e237083.2","doi-asserted-by":"crossref","DOI":"10.1186\/s13000-014-0163-2","article-title":"Deeply located low-grade fibromyxoid sarcoma with FUS-CREB3L2 gene fusion in a 5-year-old boy with review of literature","volume":"9","author":"Kurisaki-Arakawa","year":"2014","journal-title":"Diagn Pathol"},{"key":"2025082708260944000_14.5.e237083.3","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s12105-015-0647-8","article-title":"Low-Grade fibromyxoid sarcoma of the head and neck: a clinicopathologic series and review of the literature","volume":"10","author":"Cowan","year":"2016","journal-title":"Head Neck Pathol"},{"key":"2025082708260944000_14.5.e237083.4","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318210c268"},{"key":"2025082708260944000_14.5.e237083.5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/256280","article-title":"Low-Grade fibromyxoid sarcoma: incidence, treatment strategy of metastases, and clinical significance of the FUS gene","volume":"2013","author":"Maretty-Nielsen","year":"2013","journal-title":"Sarcoma"},{"key":"2025082708260944000_14.5.e237083.6","doi-asserted-by":"publisher","DOI":"10.21873\/invivo.11766"},{"key":"2025082708260944000_14.5.e237083.7","doi-asserted-by":"crossref","DOI":"10.1186\/s13256-015-0658-9","article-title":"A low grade fibromyxoid sarcoma originating from the masseter muscle: a case report","volume":"9","author":"Lee","year":"2015","journal-title":"J Med Case Rep"},{"key":"2025082708260944000_14.5.e237083.8","first-page":"1056","article-title":"Low grade fibromyxoid sarcoma of the neck: a case report","volume":"1","author":"Tatari","year":"2016","journal-title":"Ann Clin Case Rep"},{"key":"2025082708260944000_14.5.e237083.9","doi-asserted-by":"crossref","first-page":"55","DOI":"10.47102\/annals-acadmedsg.V42N1p55","article-title":"Low-Grade fibromyxoid sarcoma of the thyroid: a case report","volume":"42","author":"Dong","year":"2013","journal-title":"Ann Acad Med Singap"},{"key":"2025082708260944000_14.5.e237083.10","doi-asserted-by":"publisher","DOI":"10.21873\/invivo.11766"},{"key":"2025082708260944000_14.5.e237083.11","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31822b3687"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-237083","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:26:18Z","timestamp":1756308378000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-237083"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":11,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,5,24]]},"published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1136\/bcr-2020-237083"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-237083","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}