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To our knowledge, this is the first case of ecthyma gangrenosum secondary to <jats:italic>Pseudomonas<\/jats:italic> sepsis and concurrent invasive pulmonary aspergillosis associated with ibrutinib use.<\/jats:p>","DOI":"10.1136\/bcr-2020-237085","type":"journal-article","created":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T17:05:45Z","timestamp":1611075945000},"page":"e237085","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Ibrutinib-associated necrotic nasal lesion and pulmonary infiltrates"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3589-7351","authenticated-orcid":false,"given":"Christopher","family":"Saling","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Mayo Clinic, Phoenix, Arizona, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fionna","family":"Feller","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Mayo Clinic, Phoenix, Arizona, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6391-0349","authenticated-orcid":false,"given":"Holenarasipur R","family":"Vikram","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Mayo Clinic, Phoenix, Arizona, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,1,19]]},"reference":[{"key":"2025082712265568000_14.1.e237085.1","unstructured":"Imbruvica\u00ae (ibrutinib) [package insert on the internet]. Sunyvale (CA): Pharmacyclics LLC, 2013 [revised, 2020. Available: https:\/\/imbruvica.com\/files\/prescribing-information.pdf [Accessed May 2020]."},{"key":"2025082712265568000_14.1.e237085.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2017.04.012"},{"key":"2025082712265568000_14.1.e237085.3","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2019.219220"},{"key":"2025082712265568000_14.1.e237085.4","doi-asserted-by":"crossref","unstructured":"Risnik D , Elias E , Keitelman I . The effect of ibrutinib on neutrophil and \u03b3\u03b4 T cell functions. 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