{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:22:00Z","timestamp":1762543320418,"version":"3.44.0"},"reference-count":20,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,10,30]]},"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:p>A 59-year-old man presented to the urology department with increased urinary urgency, frequency, poor urinary flow and unintentional weight loss. He had a 25-year history of idiopathic urticaria episodes which had increased in frequency over the previous 2\u2009months. On investigation, he was found to have a raised prostate-specific antigen level. He was investigated further with a multiparametric MRI, a local anaesthetic transperineal prostate biopsy, a CT scan of chest\/abdomen\/pelvis with contrast and a nuclear medicine bone scan. He was diagnosed with metastatic adenocarcinoma of the prostate and commenced on a luteinising hormone-releasing hormone antagonist and referred to oncology for further treatment. Since starting treatment, he has experienced no further episodes of urticaria.<\/jats:p>","DOI":"10.1136\/bcr-2020-237115","type":"journal-article","created":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T15:45:52Z","timestamp":1606751152000},"page":"e237115","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Dermatological manifestation of metastatic prostate cancer"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4297-7210","authenticated-orcid":false,"given":"Julia","family":"Gibb","sequence":"first","affiliation":[{"name":"Urology, Queen Alexandra Hospital, Portsmouth, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9629-3068","authenticated-orcid":false,"given":"Omikunle","family":"Babawale","sequence":"additional","affiliation":[{"name":"Urology, Queen Alexandra Hospital, Portsmouth, UK"},{"name":"Medicine, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9698-5382","authenticated-orcid":false,"given":"Yih Chyn","family":"Phan","sequence":"additional","affiliation":[{"name":"Urology, Queen Alexandra Hospital, Portsmouth, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omer","family":"Karim","sequence":"additional","affiliation":[{"name":"Urology, Queen Alexandra Hospital, Portsmouth, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,11,30]]},"reference":[{"key":"2025082712494026000_13.11.e237115.1","unstructured":"Prostate cancer statistics [Internet] . Cancer research UK, 2020. Available: https:\/\/www.cancerresearchuk.org\/health-professional\/cancer-statistics\/statistics-by-cancer-type\/prostate-cancer#heading-Zero [Accessed 11 April 2020]."},{"key":"2025082712494026000_13.11.e237115.2","doi-asserted-by":"publisher","DOI":"10.1159\/000224860"},{"key":"2025082712494026000_13.11.e237115.3","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2010.186"},{"key":"2025082712494026000_13.11.e237115.4","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2010.0099"},{"key":"2025082712494026000_13.11.e237115.5","unstructured":"Prostate Cancer [Internet] . European association of urology, 2020. Available: https:\/\/uroweb.org\/guideline\/prostate-cancer\/ [Accessed 11 October 2020]."},{"key":"2025082712494026000_13.11.e237115.6","article-title":"The role of radical prostatectomy for the treatment of metastatic prostate cancer: a systematic review and meta-analysis","volume":"38","author":"Wang","year":"2018","journal-title":"Biosci Rep"},{"key":"2025082712494026000_13.11.e237115.7","doi-asserted-by":"crossref","first-page":"E8","DOI":"10.1111\/bju.13925","article-title":"Testing radical prostatectomy in men with prostate cancer and oligometastases to the bone: a randomized controlled feasibility trial","volume":"120","author":"Sooriakumaran","year":"2017","journal-title":"BJU Int"},{"key":"2025082712494026000_13.11.e237115.8","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/S0140-6736(20)30314-7","article-title":"Prostate-Specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective, randomised, multicentre study","volume":"395","author":"Hofman","year":"2020","journal-title":"The Lancet"},{"key":"2025082712494026000_13.11.e237115.9","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1097\/JU.0000000000000800","article-title":"Underestimation of Positron Emission Tomography\/Computerized Tomography in Assessing Tumor Burden in Prostate Cancer Nodal Recurrence: Head-to-Head Comparison of \n                  68\n               Ga-PSMA and \n                  11\n               C-Choline in a Large, Multi-Institutional Series of Extended Salvage Lymph Node Dissections","volume":"204","author":"Fossati","year":"2020","journal-title":"J Urol"},{"key":"2025082712494026000_13.11.e237115.10","unstructured":"National Institute of Neurological Disorders and Stroke [Internet] . Paraneoplastic syndromes information page. Ninds.nih.gov, 2020. Available: https:\/\/www.ninds.nih.gov\/disorders\/all-disorders\/paraneoplastic-syndromes-information-page [Accessed 13 April 2020]."},{"key":"2025082712494026000_13.11.e237115.11","doi-asserted-by":"crossref","first-page":"366","DOI":"10.5021\/ad.2012.24.3.366","article-title":"Figurate paraneoplastic urticaria and prostate cancer","volume":"24","author":"Baroni","year":"2012","journal-title":"Ann Dermatol"},{"key":"2025082712494026000_13.11.e237115.12","first-page":"409","article-title":"Paraneoplastic urticarial vasculitis and recurrence of prostatic adenocarcinoma","volume":"6","author":"Marsaudon","year":"2018","journal-title":"J Case Rep Stud"},{"key":"2025082712494026000_13.11.e237115.13","doi-asserted-by":"crossref","first-page":"e113","DOI":"10.1111\/ajd.13133","article-title":"Metastatic prostate cancer presenting as subacute cutaneous lupus erythematosus","volume":"61","author":"Phan","year":"2020","journal-title":"Australas J Dermatol"},{"key":"2025082712494026000_13.11.e237115.14","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.jdcr.2017.09.014","article-title":"Paraneoplastic psoriasis in a patient with prostate cancer","volume":"4","author":"Cadmus","year":"2018","journal-title":"JAAD Case Rep"},{"key":"2025082712494026000_13.11.e237115.15","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s00066-002-0967-y","article-title":"Paraneoplastic erythroderma in a prostate cancer patient","volume":"178","author":"Momm","year":"2002","journal-title":"Strahlenther Onkol"},{"key":"2025082712494026000_13.11.e237115.16","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1159\/000443661","article-title":"Unilateral arm urticaria presenting as a paraneoplastic manifestation of metachronous bilateral breast cancer","volume":"9","author":"Kasi","year":"2016","journal-title":"Case Rep Oncol"},{"key":"2025082712494026000_13.11.e237115.17","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jdcr.2018.10.021","article-title":"Chronic spontaneous urticaria associated with colon adenocarcinoma: a paraneoplastic manifestation? A case report and review of literature","volume":"5","author":"Santiago-V\u00e1zquez","year":"2019","journal-title":"JAAD Case Rep"},{"key":"2025082712494026000_13.11.e237115.18","unstructured":"DermNet NZ [Internet] . Chronic urticaria Dermnetnz.org, 2020. Available: https:\/\/dermnetnz.org\/topics\/chronic-urticaria\/ [Accessed 11 April 2020]."},{"key":"2025082712494026000_13.11.e237115.19","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1365-2133.1990.tb01449.x","article-title":"Chronic urticaria and cancer: an epidemiological study of 1155 patients","volume":"123","author":"Lindel\u00f6f","year":"1990","journal-title":"Br J Dermatol"},{"key":"2025082712494026000_13.11.e237115.20","doi-asserted-by":"crossref","DOI":"10.1001\/archdermatol.2011.682","article-title":"Cancer risk in patients with chronic urticaria","volume":"148","author":"Chen","year":"2012","journal-title":"Arch Dermatol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-237115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T19:49:50Z","timestamp":1756324190000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-237115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":20,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2020,11,30]]},"published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1136\/bcr-2020-237115"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-237115","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2020,11]]}}}