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On optical coherence tomography, subretinal fluid in the perifoveal area was visible on the right eye, with corresponding enlargement of the visual field defect. An increased choroidal thickness was also visible. Fluorescein angiography revealed, on the right eye, two pinpoint areas of leakage and indocyanine green angiography signs of choroidal vascular hyperpermeability. Considering a diagnosis of a non-central central serous chorioretinopathy, corticosteroids use was interrupted, with resolution of the subretinal fluid. This case illustrates the relevance of a multimodal imaging approach to guide the diagnosis of patient with an SLE with subretinal fluid.<\/jats:p>","DOI":"10.1136\/bcr-2020-237243","type":"journal-article","created":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T11:58:19Z","timestamp":1610971099000},"page":"e237243","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Non-central serous chorioretinopathy in a patient with systemic lupus erythematosus and hydroxychloroquine retinopathy"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5972-4068","authenticated-orcid":false,"given":"Diogo","family":"Hipolito-Fernandes","sequence":"first","affiliation":[{"name":"Ophthalmology, Centro Hospitalar de Lisboa Central EPE, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9361-089X","authenticated-orcid":false,"given":"Maria Elisa","family":"Lu\u00eds","sequence":"additional","affiliation":[{"name":"Ophthalmology, Centro Hospitalar de Lisboa Central EPE, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Flores","sequence":"additional","affiliation":[{"name":"Ophthalmology, Centro Hospitalar de Lisboa Central EPE, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Anjos","sequence":"additional","affiliation":[{"name":"Ophthalmology, Centro Hospitalar de Lisboa Central EPE, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,1,18]]},"reference":[{"key":"2025082703562565000_14.1.e237243.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(99)00075-6"},{"key":"2025082703562565000_14.1.e237243.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2007.02.032"},{"key":"2025082703562565000_14.1.e237243.3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/IAE.0000000000000837","article-title":"Risk factors for central serous chorioretinopathy","volume":"36","author":"Liu","year":"2016","journal-title":"Retina"},{"key":"2025082703562565000_14.1.e237243.4","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-018-0158-4"},{"key":"2025082703562565000_14.1.e237243.5","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2015-306629"},{"key":"2025082703562565000_14.1.e237243.6","unstructured":"The Royal College of Ophthalmologists . 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