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This caused a small volume right to left shunt. The persistent left SVC drained into the right atrium (RA) via a dilated coronary sinus. The overall clinical impression was recurrent paradoxical emboli due to anomalous venous anatomy with a thrombophilia secondary to sickle cell trait. In the normal embryo, the right common cardinal vein develops to become the RSVC, which drains into the RA by term.<\/jats:p>","DOI":"10.1136\/bcr-2020-237401","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T15:22:39Z","timestamp":1612192959000},"page":"e237401","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Multiple thromboembolic events associated with bilateral superior vena cava and anomalous drainage into the left atrium"],"prefix":"10.1136","volume":"14","author":[{"given":"Maria Elizabeth","family":"Karavassilis","sequence":"first","affiliation":[{"name":"Intensive Care Unit, West Hertfordshire Hospitals NHS Trust, Watford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Haji-Coll","sequence":"additional","affiliation":[{"name":"Stroke Medicine, West Hertfordshire Hospitals NHS Trust, Watford, Hertfordshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niall G","family":"Keenan","sequence":"additional","affiliation":[{"name":"Cardiology, West Hertfordshire Hospitals NHS Trust, Watford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,2,1]]},"reference":[{"key":"2025082700500680000_14.2.e237401.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1700365"},{"key":"2025082700500680000_14.2.e237401.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.04.063"},{"key":"2025082700500680000_14.2.e237401.3","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/j.2205-0140.2012.tb00228.x","article-title":"Persistent left superior vena cava - 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