{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T07:10:20Z","timestamp":1756278620338,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,12,10]]},"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>A 43-year-old man presented to hospital after routine laboratory tests showed an acute kidney injury and hypercalcaemia. He had no relevant medical history and normal physical examination, other than a 6-week history of lower back pain for which he had been taking naproxen. Low parathyroid hormone (PTH) levels indicated a PTH-independent hypercalcaemia. Investigations including CT of thorax, abdomen and pelvis and subsequent bone biopsy and renal biopsy were unremarkable. Positron emission tomography\/CT (PET\/CT) scan was ultimately considered as a diagnostic test and showed abnormalities in the right subpectoral and portacaval region with intense fluorodeoxyglucose F 18 uptake in local lymph nodes. A biopsy of the right subpectoral node showed granulomatous change consistent with sarcoidosis. PET\/CT scanning can play an important role in the investigation of suspected malignancy, infection and inflammatory disease and in this case, was required to diagnose an atypical presentation of sarcoidosis.<\/jats:p>","DOI":"10.1136\/bcr-2020-237424","type":"journal-article","created":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T14:07:39Z","timestamp":1610028459000},"page":"e237424","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Unusual presentation of sarcoidosis, requiring a positron emission tomography\/CT (PET\/CT) for diagnosis"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8867-1364","authenticated-orcid":false,"given":"Kenneth","family":"O'Riordan","sequence":"first","affiliation":[{"name":"Medicine, Nenagh General Hospital, Nenagh, Tipperary, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tauseef","family":"Mohyuddin","sequence":"additional","affiliation":[{"name":"Gastroenterology, Nenagh General Hospital, Nenagh, Tipperary, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manus","family":"Moloney","sequence":"additional","affiliation":[{"name":"Gastroenterology, Nenagh General Hospital, Nenagh, Tipperary, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,1,7]]},"reference":[{"key":"2025082623375518000_14.1.e237424.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra071714"},{"key":"2025082623375518000_14.1.e237424.2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.160.2.ats4-99"},{"key":"2025082623375518000_14.1.e237424.3","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1148\/rg.2018180053","article-title":"PET\/CT in the diagnosis and workup of sarcoidosis: focus on atypical manifestations","volume":"38","author":"Akaike","year":"2018","journal-title":"Radiographics"},{"key":"2025082623375518000_14.1.e237424.4","doi-asserted-by":"crossref","first-page":"13","DOI":"10.4103\/0971-6203.25665","article-title":"Positron emission tomography: an overview","volume":"31","author":"Shukla","year":"2006","journal-title":"J Med Phys"},{"key":"2025082623375518000_14.1.e237424.5","doi-asserted-by":"crossref","first-page":"890","DOI":"10.3390\/jcm9030890","article-title":"In which patients with sarcoidosis is FDG PET\/CT indicated?","volume":"9","author":"Keijsers","year":"2020","journal-title":"J Clin Med"},{"key":"2025082623375518000_14.1.e237424.6","doi-asserted-by":"publisher","DOI":"10.1097\/MCP.0b013e328363ed0d"},{"key":"2025082623375518000_14.1.e237424.7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-1178"},{"key":"2025082623375518000_14.1.e237424.8","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.111.090662"},{"key":"2025082623375518000_14.1.e237424.9","first-page":"255","article-title":"An update on the role of \n                  18\n               F-FDG-PET\/CT in major infectious and inflammatory diseases","volume":"9","author":"Kung","year":"2019","journal-title":"Am J Nucl Med Mol Imaging"},{"key":"2025082623375518000_14.1.e237424.10","doi-asserted-by":"crossref","first-page":"32","DOI":"10.2174\/1573405614666180522075828","article-title":"Diagnostic Performance of 18 F-FDG PET\/CT Semiquantitative Analysis in the Management of Sarcoidosis","volume":"15","author":"Rubini","year":"2019","journal-title":"Curr Med Imaging Rev"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-237424","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T06:38:03Z","timestamp":1756276683000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-237424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,1,7]]},"published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1136\/bcr-2020-237424"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-237424","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}