{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:40:19Z","timestamp":1756305619463,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,11,30]]},"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:p>A 44-year-old Asian Indian woman presented with a history of pain and redness in the left eye for 3\u2009weeks. Scleral congestion with a nodular swelling was present inferotemporally. Raised C reactive protein and positive antinuclear and perinuclear antineutrophil cytoplasmic antibodies suggested autoimmune scleritis. The patient was therefore managed with corticosteroids. Nevertheless, the development of severe pain associated with a scleral abscess led to a revised diagnosis of infectious scleritis. Corticosteroids therapy was halted and urgent debridement was performed. Microbiology confirmed fungal scleritis due to <jats:italic>Coprinopsis cinerea<\/jats:italic>. Multiple full-thickness circumferential debridements with antifungal therapy resulted in satisfactory anatomical and visual outcomes. This case presented a unique challenge, since laboratory results were misleading, and corticosteroids resulted in a fulminant clinical course. Therefore, aggressive circumferential debridement was performed to achieve the elimination of a rare fungal aetiology of scleritis, which has not been reported previously to cause human infection.<\/jats:p>","DOI":"10.1136\/bcr-2020-237586","type":"journal-article","created":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T12:23:14Z","timestamp":1609158194000},"page":"e237586","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Necrotising fungal scleritis with full-thickness scleral melt and circumferential progression: a novel debridement approach"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6991-4746","authenticated-orcid":false,"given":"Samendra","family":"Karkhur","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, 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