{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T14:02:17Z","timestamp":1784383337232,"version":"3.55.0"},"reference-count":16,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,12,17]]},"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:p>A 40-year-old woman was referred to infectious disease specialists for a <jats:italic>Mycobacterium mageritense<\/jats:italic> skin infection following mastectomy and bilateral reconstruction with deep inferior epigastric perforator flap. Her case demonstrates the difficulty in treating non-tuberculosis mycobacterial infections, especially the rarely seen species. She failed to respond to dual antibiotic therapy containing imipenem-cilastin despite reported sensitivity. Additionally, her course was complicated by intolerance to various regimens, including gastrointestinal distress, a drug rash with eosinophilia and systemic symptoms, and tendinopathy. With few published data, no treatment guidelines, and limited medications from which to choose for <jats:italic>M. mageritense,<\/jats:italic> her treatment posed a challenge. She ultimately required aggressive surgical intervention and a triple therapy antibiotic regimen. The duration of our patient\u2019s treatment and the extent of her complications suggest a potential need for early surgical intervention in postsurgical wounds infected with <jats:italic>M. mageritense<\/jats:italic> that do not respond to conventional treatment.<\/jats:p>","DOI":"10.1136\/bcr-2020-237618","type":"journal-article","created":{"date-parts":[[2021,2,4]],"date-time":"2021-02-04T17:40:16Z","timestamp":1612460416000},"page":"e237618","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["<i>Mycobacterium mageritense<\/i> infection following mastectomy and breast reconstruction requiring triple antibiotic therapy and surgical debridement"],"prefix":"10.1136","volume":"14","author":[{"given":"Christie Alyce","family":"Joya","sequence":"first","affiliation":[{"name":"Parasitology, Naval Medical Research Unit No 6, Callao, Peru"},{"name":"Infectious Disease, Walter Reed National Military Medical Center, Bethesda, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3139-9491","authenticated-orcid":false,"given":"Cara","family":"Deegan","sequence":"additional","affiliation":[{"name":"School of Medicine, USUHS, Bethesda, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd D","family":"Gleeson","sequence":"additional","affiliation":[{"name":"Infectious Disease, Walter Reed National Military Medical Center, Bethesda, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,2,4]]},"reference":[{"key":"2025082709394858000_14.2.e237618.1","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-47-2-535"},{"key":"2025082709394858000_14.2.e237618.2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.8.2930-2935.2002"},{"key":"2025082709394858000_14.2.e237618.3","unstructured":"Center for Disease Control and Prevention . Nontuberculous mycobacteria (NTM) infections, 2019. Available: https:\/\/www.cdc.gov\/hai\/organisms\/nontuberculous-mycobacteria.html [Accessed 12 Nov 2020]."},{"key":"2025082709394858000_14.2.e237618.4","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.4.1813-1817.2004"},{"key":"2025082709394858000_14.2.e237618.5","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01224-06"},{"key":"2025082709394858000_14.2.e237618.6","doi-asserted-by":"publisher","DOI":"10.1086\/589300"},{"key":"2025082709394858000_14.2.e237618.7","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-008-0521-7"},{"key":"2025082709394858000_14.2.e237618.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.eimc.2012.05.007"},{"key":"2025082709394858000_14.2.e237618.9","first-page":"34","article-title":"A case of surgical site infection by Mycobacterium mageritense after gastrectomy","volume":"23","author":"Yonetani","year":"2013","journal-title":"The Journal of Japanese Society for Clinical Microbiology"},{"key":"2025082709394858000_14.2.e237618.10","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01041-15"},{"key":"2025082709394858000_14.2.e237618.11","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.jiac.2015.09.010","article-title":"Implantable cardioverter defibrillator infection due to Mycobacterium mageritense","volume":"22","author":"Fukunaga","year":"2016","journal-title":"J Infect Chemother"},{"key":"2025082709394858000_14.2.e237618.12","doi-asserted-by":"crossref","first-page":"283","DOI":"10.4172\/2332-0877.1000283","article-title":"Surgical site infection due to Mycobacterium mageritense and literature review","volume":"4","author":"Ogawa","year":"2016","journal-title":"J Infect Dis Ther"},{"key":"2025082709394858000_14.2.e237618.13","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/s12088-017-0692-y","article-title":"Mycobacterium mageritense Parotitis in an Immunocompetent Adult","volume":"58","author":"Okabe","year":"2018","journal-title":"Indian J Microbiol"},{"key":"2025082709394858000_14.2.e237618.14","doi-asserted-by":"crossref","first-page":"987","DOI":"10.2340\/00015555-3005","article-title":"A case of subcutaneous infection with Mycobacterium mageritense identified by matrix-assisted laser desorption\/ionization-time of flight mass spectrometry","volume":"98","author":"Oiwa","year":"2018","journal-title":"Acta Derm Venereol"},{"key":"2025082709394858000_14.2.e237618.15","doi-asserted-by":"crossref","first-page":"369","DOI":"10.22270\/jddt.v9i1-s.2386","article-title":"Infection of Mycobacterium mageritense at surgical site: a first case report of India","volume":"9","author":"Shah","year":"2019","journal-title":"J drug deliv ther"},{"key":"2025082709394858000_14.2.e237618.16","unstructured":"Singhal L et al . Multiple recalcitrant draining sinuses following laparoscopic cholecystectomy by Mycobacterium mageritense: case report and brief review of literature. Jpn J Infect Dis 2020;343."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-237618","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:39:54Z","timestamp":1756312794000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-237618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":16,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,2,4]]},"published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1136\/bcr-2020-237618"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-237618","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2]]}}}