{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T13:33:39Z","timestamp":1767965619883,"version":"3.49.0"},"reference-count":20,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,5,13]]},"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:p>Infective endocarditis is associated with morbidity and mortality even when appropriately treated. It can be more complicated to treat when prosthetic material is present, often necessitating surgical revision as well as antimicrobial therapy. Endocarditis caused by gram-negative bacilli is a rare occurrence, with some literature and expert opinion suggesting superior outcomes with combined surgery and antibiotics when a prosthetic valve is involved. In cases where the prosthetic valve is well-functioning and undamaged, or cardiothoracic surgery represents a significant operative risk, it can be unclear how best to proceed. This report documents a case of <jats:italic>Salmonella enterica<\/jats:italic> subspecies <jats:italic>enterica<\/jats:italic> serovar <jats:italic>enteritidis<\/jats:italic> endocarditis of a mechanical mitral valve. The patient was managed with 6\u2009weeks of intravenous antibiotics followed by suppressive oral antibiotic therapy. They remain in good health at 24 months.<\/jats:p>","DOI":"10.1136\/bcr-2020-237679","type":"journal-article","created":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T11:45:27Z","timestamp":1624448727000},"page":"e237679","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Medically managed prosthetic valve endocarditis caused by <i>Salmonella enteritidis<\/i>"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3930-5341","authenticated-orcid":false,"given":"Gavin","family":"Connolly","sequence":"first","affiliation":[{"name":"Infectious Diseases, Northern Care Alliance NHS Group, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mita","family":"Kale","sequence":"additional","affiliation":[{"name":"Cardiology, Northern Care Alliance NHS Group, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Ustianowski","sequence":"additional","affiliation":[{"name":"Infectious Diseases, Northern Care Alliance NHS Group, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,6,23]]},"reference":[{"key":"2025082803411740000_14.6.e237679.1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkr450"},{"key":"2025082803411740000_14.6.e237679.2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-147-12-200712180-00002"},{"key":"2025082803411740000_14.6.e237679.3","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.02208-17","article-title":"Risk factors and outcomes of endocarditis due to Non-HACEK gram-negative bacilli: data from the prospective multicenter Italian endocarditis study cohort","volume":"62","author":"Falcone","year":"2018","journal-title":"Antimicrob Agents Chemother"},{"key":"2025082803411740000_14.6.e237679.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2008.03.012"},{"key":"2025082803411740000_14.6.e237679.5","doi-asserted-by":"crossref","first-page":"889","DOI":"10.3109\/23744235.2015.1075660","article-title":"Endocarditis due to gram-negative bacilli at a French teaching hospital over a 6-year period: clinical characteristics and outcome","volume":"47","author":"Loubet","year":"2015","journal-title":"Infect Dis"},{"key":"2025082803411740000_14.6.e237679.6","doi-asserted-by":"publisher","DOI":"10.1097\/01.md.0000125652.75260.cf"},{"key":"2025082803411740000_14.6.e237679.7","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2008.603"},{"key":"2025082803411740000_14.6.e237679.8","article-title":"The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2017\/2018","volume":"18","year":"2020","journal-title":"Efsa J"},{"key":"2025082803411740000_14.6.e237679.9","unstructured":"Jenkins C . Salmonella: Enteric fever; gastrointestinal infection; food poisoning. In: Barer M , Irving WL , Swann A , et al , eds. Medical microbiology: a guide to microbial infections. 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