{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:02:17Z","timestamp":1756339337555,"version":"3.44.0"},"reference-count":14,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,12,17]]},"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Hyponatraemia is one of the most common and serious electrolyte abnormalities in patients with neurological diseases. Assessing the intravascular fluid status, urine sodium, urine and serum osmolality helps to narrow down the differential diagnosis. Differentiation between cerebral salt-wasting syndrome (CSWS), diabetes insipidus and syndrome of inappropriate antidiuretic hormone (SIADH) secretion is absolutely necessary for correct management of hyponatraemia in this group of patients. In this case report, we have presented a 46-year-old gentleman who was admitted to intensive care unit (ICU) with status epilepticus and developed hyponatraemia during course of his ICU stay, diagnosed as CSWS and managed with normal saline and fludrocortisone. His serum sodium gradually improved, consciousness was regained and later shifted to general ward on antiepileptic treatment.<\/jats:p>","DOI":"10.1136\/bcr-2020-237740","type":"journal-article","created":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T12:09:41Z","timestamp":1610971781000},"page":"e237740","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Cerebral salt-wasting syndrome in a patient with status epilepticus: a rare association"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8292-9942","authenticated-orcid":false,"given":"Sudheer","family":"Tale","sequence":"first","affiliation":[{"name":"Pulmonary and Critical Care Medicine, AIIMS Rishikesh, Rishikesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mrudula","family":"Kolli","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Medicine, AIIMS Rishikesh, Rishikesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kesari","family":"Masaipeta","sequence":"additional","affiliation":[{"name":"Critical Care Medicine, AIIMS Rishikesh, Rishikesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7593-8640","authenticated-orcid":false,"given":"Gautam Vinay Kumar","family":"Budumuri","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, AIIMS Rishikesh, Rishikesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,1,18]]},"reference":[{"key":"2025082622511204000_14.1.e237740.1","doi-asserted-by":"publisher","DOI":"10.1159\/000048356"},{"key":"2025082622511204000_14.1.e237740.2","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e328305e403"},{"key":"2025082622511204000_14.1.e237740.3","doi-asserted-by":"crossref","first-page":"506","DOI":"10.3171\/jns.1971.34.4.0506","article-title":"Neurosurgical hyponatremia: the role of inappropriate antidiuresis","volume":"34","author":"Fox","year":"1971","journal-title":"J Neurosurg"},{"key":"2025082622511204000_14.1.e237740.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(05)70535-6"},{"key":"2025082622511204000_14.1.e237740.5","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5001845"},{"key":"2025082622511204000_14.1.e237740.6","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.pediatrneurol.2013.11.019","article-title":"Cerebral salt wasting in status epilepticus: two cases and review of the literature","volume":"50","author":"\u00c7elik","year":"2014","journal-title":"Pediatr Neurol"},{"key":"2025082622511204000_14.1.e237740.7","unstructured":"Tenny S , Thorell W . 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