{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:40:04Z","timestamp":1756312804107,"version":"3.44.0"},"reference-count":19,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,4,28]]},"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p>The objective of this article is to elucidate on our experience with the first case reported in the literature of a synchronous presentation of pleomorphic adenoma (PA) in infratemporal fossa as well as the contralateral submandibular gland. PA most commonly arises from the major salivary glands but has also been reported to arise from minor salivary glands in unusual sites such as the nasal septum, main stem bronchus, trachea, lacrimal gland, external auditory canal, etc. However, it seldom involves the infratemporal fossa and extremely few cases are reported in the literature and coexistent contralateral synchronous PA is nowhere reported in literature. The infratemporal fossa tumour posed a diagnostic dilemma and therapeutic challenge because of its concealed location which we dealt successfully with endoscopic sublabial trans maxillary approach.<\/jats:p>","DOI":"10.1136\/bcr-2020-237775","type":"journal-article","created":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T12:15:58Z","timestamp":1621599358000},"page":"e237775","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Synchronous pleomorphic adenoma in the infratemporal fossa and contralateral submandibular gland and endoscopic removal"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1897-3970","authenticated-orcid":false,"given":"Shahul Hameed","family":"Poondiyar Sirajuddin","sequence":"first","affiliation":[{"name":"Ears Nose and Throat (ENT), East Surrey Hospital, Redhill, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rayappa","family":"Chunnusamy","sequence":"additional","affiliation":[{"name":"Department of ENT and Head and Neck Surgery, Apollo Specialty Cancer Hospital, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,5,21]]},"reference":[{"key":"2025082709101921000_14.5.e237775.1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s12105-007-0036-z","article-title":"Pleomorphic adenoma in the infra-temporal space: the first case report","volume":"1","author":"Jeyanthi","year":"2007","journal-title":"Head Neck Pathol"},{"key":"2025082709101921000_14.5.e237775.2","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0385-8146(03)00090-7","article-title":"Pleomorphic adenoma originated from the inferior nasal turbinate","volume":"30","author":"Unlu","year":"2003","journal-title":"Auris Nasus Larynx"},{"key":"2025082709101921000_14.5.e237775.3","doi-asserted-by":"crossref","DOI":"10.1002\/lary.21615","article-title":"Pleomorphic adenoma of the infratemporal fossa: case report and literature review","volume":"120","author":"Gurey","year":"2010","journal-title":"Laryngoscope"},{"key":"2025082709101921000_14.5.e237775.4","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s11282-016-0262-8","article-title":"Carcinoma ex pleomorphic adenoma of the infratemporal fossa: a case report with magnetic resonance imaging findings","volume":"33","author":"Tanrivermis Sayit","year":"2017","journal-title":"Oral Radiol"},{"key":"2025082709101921000_14.5.e237775.5","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/s12070-018-1488-z","article-title":"Cystic Myoepithelioma of parapharyngeal space","volume":"71","author":"Veluswamy","year":"2019","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"2025082709101921000_14.5.e237775.6","doi-asserted-by":"crossref","first-page":"740","DOI":"10.3950\/jibiinkoka.93.740","article-title":"[A rare case of pleomorphic adenoma of lateral wall of nasal cavity--with special reference of statistical observation of pleomorphic adenoma of nasal cavity in Japan]","volume":"93","author":"Suzuki","year":"1990","journal-title":"Nihon Jibiinkoka Gakkai Kaiho"},{"key":"2025082709101921000_14.5.e237775.7","first-page":"166","volume-title":"Surgical pathology of salivary gland","volume":"25","author":"Ellis","year":"1991"},{"key":"2025082709101921000_14.5.e237775.8","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1053\/joms.2000.9587","article-title":"Giant parotid pleomorphic adenoma involving the parapharyngeal space: report of a case","volume":"58","author":"Rodr\u00edguez-Ciurana","year":"2000","journal-title":"J Oral Maxillofac Surg"},{"key":"2025082709101921000_14.5.e237775.9","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1055\/s-0034-1378184","article-title":"Remarkable triple pleomorphic adenoma affecting both parotid and submandibular glands","volume":"8","author":"Pingarr\u00f3n-Mart\u00edn","year":"2015","journal-title":"Craniomaxillofac Trauma Reconstr"},{"key":"2025082709101921000_14.5.e237775.10","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s00276-003-0126-x","article-title":"A cadaveric study of a combined trans-mandibular and trans-zygomatic approach to the infratemporal fossa","volume":"25","author":"Prades","year":"2003","journal-title":"Surg Radiol Anat"},{"key":"2025082709101921000_14.5.e237775.11","unstructured":"Heeneman H . Parapharyngeal space tumours. In: Kerr AG , ed. Scott Brown\u2019s otolaryngology. Butterworth & Co Ltd, 1987: 380\u201391."},{"key":"2025082709101921000_14.5.e237775.12","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-6789"},{"key":"2025082709101921000_14.5.e237775.13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1985.tb00522.x"},{"key":"2025082709101921000_14.5.e237775.14","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-985193"},{"key":"2025082709101921000_14.5.e237775.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.03.063"},{"key":"2025082709101921000_14.5.e237775.16","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.4.441"},{"key":"2025082709101921000_14.5.e237775.17","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e318155a492"},{"key":"2025082709101921000_14.5.e237775.18","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ajme.2013.12.001","article-title":"Endoscopic approach to the infratemporal fossa","volume":"50","author":"Youssef","year":"2014","journal-title":"Alexandria J Med"},{"key":"2025082709101921000_14.5.e237775.19","first-page":"1","article-title":"Expanded endonasal approach: fully endoscopic, completely transnasal approach to the middle third of the clivus, petrous bone, middle cranial fossa, and infratemporal fossa","volume":"19","author":"Kassam","year":"2005","journal-title":"Neurosurg Focus"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-237775","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:10:29Z","timestamp":1756311029000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-237775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":19,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,5,21]]},"published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1136\/bcr-2020-237775"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-237775","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}