{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:05:27Z","timestamp":1790665527840,"version":"4.1.0"},"reference-count":18,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,11,30]]},"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>We describe the case of <jats:italic>Mycoplasma hominis<\/jats:italic> septic arthritis in a 58-year-old woman with a history of rheumatoid arthritis and ulcerative colitis on immunosuppressive therapy with rituximab. Treatment with anti-CD20 antibodies (eg, rituximab) leads to an immediate depletion of B cells and hence risk of reductions in immunoglobulins and increased risk of infections. This effect may last long after drug cessation. <jats:italic>M. hominis<\/jats:italic> is commensal to the genitourinary tract in sexually active adults. Extragenital <jats:italic>M. hominis<\/jats:italic> infections including septic arthritis are rare, but hypogammaglobulinaemia is a predisposing factor. As <jats:italic>M. hominis<\/jats:italic> requires extended culture, special media or PCR analysis, it is not tested routinely, which in many cases delays diagnosis and correct treatment. In our case, a diagnosis of <jats:italic>M. hominis<\/jats:italic> septic arthritis was made after 9 weeks by PCR analysis and culture of joint fluid. The patient responded well to an 8-week treatment course of moxifloxacin and doxycycline.<\/jats:p>","DOI":"10.1136\/bcr-2020-237798","type":"journal-article","created":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T17:05:39Z","timestamp":1611075939000},"page":"e237798","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["<i>Mycoplasma hominis<\/i> septic arthritis in a patient with hypogammaglobinaemia and rheumatoid arthritis"],"prefix":"10.1136","volume":"14","author":[{"given":"Naila","family":"Bozo","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Odense University Hospital, Odense, Fyn, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christen","family":"Ravn","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Odense University Hospital, Odense, Fyn, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrik Stenz","family":"Justesen","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, Odense University Hospital, Odense, Fyn, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Line","family":"Dahlerup Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Odense University Hospital, Odense, Fyn, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,1,19]]},"reference":[{"key":"2025082712095837000_14.1.e237798.1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00006-11"},{"key":"2025082712095837000_14.1.e237798.2","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-019-3686-z","article-title":"Infection due to Mycoplasma hominis after left hip replacement: case report and literature review","volume":"19","author":"Xiang","year":"2019","journal-title":"BMC Infect Dis"},{"key":"2025082712095837000_14.1.e237798.3","unstructured":"Pereyre S , Bebear C , Bebear CM . 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