{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T14:23:04Z","timestamp":1771856584393,"version":"3.50.1"},"reference-count":19,"publisher":"BMJ","issue":"2","license":[{"start":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T00:00:00Z","timestamp":1613606400000},"content-version":"unspecified","delay-in-days":17,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,1,25]]},"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:p>Both insufficient and excessive maternal iodine consumption can result in congenital hypothyroidism. In East Asian cultures, seaweed is traditionally consumed in high quantities by peripartum women as it is thought to improve lactation. We present a case of transient congenital hypothyroidism due to maternal seaweed consumption at a daily basis during pregnancy and lactation in a Dutch family without Asian background. This case highlights that even in families of non-Asian background, high maternal intake of iodine-rich seaweed occurs and can result in transient or permanent hyperthyrotropinemia in the neonate with risk of impaired neurodevelopmental outcome if untreated.<\/jats:p>","DOI":"10.1136\/bcr-2020-237930","type":"journal-article","created":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T11:10:04Z","timestamp":1613733004000},"page":"e237930","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Unusual cause of congenital hypothyroidism in a term infant"],"prefix":"10.1136","volume":"14","author":[{"given":"Hester","family":"Vlaardingerbroek","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Subdivision of Endocrinology, Willem Alexander Children's Hospital, LUMC, Leiden, The Netherlands"},{"name":"Department of Pediatrics, Subdivision of Endocrinology, Sophia Children's Hospital, Erasmus Medical Centre, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,2,19]]},"reference":[{"key":"2025082801540821000_14.2.e237930.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(70)91736-8"},{"key":"2025082801540821000_14.2.e237930.2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.63.10.1207"},{"key":"2025082801540821000_14.2.e237930.3","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(69)90245-9"},{"key":"2025082801540821000_14.2.e237930.4","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2004.14.1077"},{"key":"2025082801540821000_14.2.e237930.5","unstructured":"Survey of iodine levels in seaweed and seaweed containing products in Australia. Available: https:\/\/www.foodstandards.gov.au\/science\/surveillance\/documents\/Iodine%20in%20Seaweed.pdf"},{"key":"2025082801540821000_14.2.e237930.6","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2004.14.836"},{"key":"2025082801540821000_14.2.e237930.7","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1089\/thy.2011.0084","article-title":"High iodine content of Korean seaweed soup: a health risk for lactating women and their infants?","volume":"21","author":"Rhee","year":"2011","journal-title":"Thyroid"},{"key":"2025082801540821000_14.2.e237930.8","doi-asserted-by":"crossref","unstructured":"Nordic Council of Ministers (Nordic Council of Ministers) . Nordic nutrition recommendations 2012; integrating nutrition and physical activity 2014;5:p. 627.","DOI":"10.26530\/OAPEN_483279"},{"key":"2025082801540821000_14.2.e237930.9","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.116.134049"},{"key":"2025082801540821000_14.2.e237930.10","unstructured":"National Institutes of health OoDS. iodine, fact sheet for health professionals 2018. Available: https:\/\/ods.od.nih.gov\/factsheets\/Iodine-HealthProfessional\/"},{"key":"2025082801540821000_14.2.e237930.11","first-page":"p. 3660","article-title":"Scientific opinion on dietary reference values for iodine","volume":"12","year":"2014","journal-title":"EFSA Journal"},{"key":"2025082801540821000_14.2.e237930.12","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1017\/S1368980007361004","article-title":"Prevention and control of iodine deficiency in pregnant and lactating women and in children less than 2-years-old: conclusions and recommendations of the technical consultation","volume":"10","author":"Andersson","year":"2007","journal-title":"Public Health Nutr"},{"key":"2025082801540821000_14.2.e237930.13","article-title":"Correction: impact of seaweed intake on health","author":"Murai","year":"2020","journal-title":"Eur J Clin Nutr"},{"key":"2025082801540821000_14.2.e237930.14","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0632"},{"key":"2025082801540821000_14.2.e237930.15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2010.01972.x"},{"key":"2025082801540821000_14.2.e237930.16","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1515\/jpem-2018-0138","article-title":"Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism","volume":"31","author":"Hamby","year":"2018","journal-title":"J Pediatr Endocrinol Metab"},{"key":"2025082801540821000_14.2.e237930.17","doi-asserted-by":"publisher","DOI":"10.1159\/000339157"},{"key":"2025082801540821000_14.2.e237930.18","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2019.00109","article-title":"Subclinical hypothyroidism in children: when a replacement hormonal treatment might be advisable","volume":"10","author":"Crisafulli","year":"2019","journal-title":"Front Endocrinol"},{"key":"2025082801540821000_14.2.e237930.19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2016.04.011"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-237930","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:54:17Z","timestamp":1756371257000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-237930"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":19,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,2,19]]},"published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1136\/bcr-2020-237930"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-237930","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2]]}}}